发热伴血小板减少综合征流行病学研究进展

A review on the epidemiologic features of severe fever with thrombocytopenia syndrome

发热伴血小板减少综合征（SFTS）是我国中东部农村地区新出现的由布尼亚病毒（SFTSV）感染引起的发热伴血小板减少综合征。蜱叮咬是其主要传播途径,可通过人-人接触传播。该病起病急,病情进展较快,主要临床表现为发热、血小板减少、白细胞减少以及胃肠、肝肾功能异常等,部分患者可因多脏器功能衰竭而死亡,平均报告病死率约10%。本文采用查阅文献资料的方法,对近年来该病的流行分布特点以及传播媒介、宿主动物、传播途径和人群易感性的最新研究进展做一综述。

Severe fever with Thrombocytopenia Syndrome（SFTS） is an emerging hemorrhagic fever disease in the rural areas of east-central China, which is caused by SFTSV-a newly discovered bunyavirus.SFTSV is most likely transmitted by tick bites but can also be transmitted within human beings.The onset of SFTS is sudden and with rapid progress, with main clinical manifestations as fever, thrombocytopenia, leucopenia and gastrointestinal and hepatorenal dysfunctions.Some patients may die from multiple organ failure, and the case fatality rate is approximately 10%.In this paper, we use the method of literature review to summarize the recent research progress of SFTS which includes the epidemic distribution characteristics, medium of transmission, host animals, transmission routes and susceptibility in the general population.