1例同时性肝转移结肠癌患者的MDT诊治报道

MDT diagnosis and treatment of colonic cancer with synchronous liver metastases: A case review

本文介绍1例同时性肝转移结肠癌病例的多学科诊治过程。该病例初诊时肝脏多发转移无法切除,经过多学科讨论后患者接受化疗联合靶向药物治疗,意外实现肝脏转移灶和结肠原发灶的切除。术后9月,患者肝脏转移癌复发,经过多学科讨论治疗后再次获得缓解。该病例的诊治过程说明,多学科诊治对于改善结直肠癌肝转移患者的生存至关重要;初始不可切除的肝转移患者应根据其耐受性和治疗的反应情况动态调整治疗目标。多学科诊治团队需常态化和专业化以实现患者的最大获益。

The history of multidisciplinary team（ MDT） treatment of a colonic cancer patient with synchronous multiple liver metastases was described. Liver metastases were unresectable at initial diagnosis. The patient received chemotherapy combined with targeted therapy after MDT discussion. The patient attained occasional partial response（ PR） and received hepatectomy and colectomy. The hepatic recurrence was confirmed 9 months after surgery. PR was achieved again by chemotherapy combined with targeted therapy. The case indicated that MDT discussion was key to improve the prognosis of patients with liver metastases of colorectal cancer. Treatment aim should be dynamically adjusted according to the tolerance and treatment response of patients. MDT should be stable and specialized to achieve patients＇ maximum benefit.