1Zhang Y, Proenca R, Mallei M, et al. Positional cloning of the mouse obese gene and its human homologue [J]. Nature, 1994, 372 (6505) : 425 -432.
2Friedman J M, Halaas J L. Leptin and the regulation of body weight in mam- mals [J]. Nature, 1998, 395 (6704) : 763 -770.
3Considine R V, Sinha M K, Heiman M L, et al. Serum immunoreactive -leptin concentrations in normal - weight and obese humans [J]. New England Journal of Medicine, 1996, 334 (5) : 292 -295.
4Dyer C J, Simmons J M, Matted R L, et al. eDNA cloning and tissue -spe- cific gane expression of ovine leptin, NPY - Y1 receptor, and NPY - Y2 receptor [J]. Domestic animal endocrinology, 1997, 14 (5): 295-303.
5Pelleymounter M A, Cullen M J, Baker M B, et al. Effects of the obese gene product on body weight regulation in ob/ob mice [J]. Science, 1995, 269 (5223) : 540 - 543.
6Arble D M, Vitatema M H, Turek F W. Rhythmic leptin is required for weight gain from circadian desynehronized feeding in the mouse [J]. PloS one, 2011,6 (9) : e25079.
8Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth - hormone - relea- sing acylated poptide from stomach [J]. Nature, 1999, 402 (6762) : 656 -660.
9Tschp M, Smiley D L, Heiman M L. Ghrelin induces adiposity in rodents [J]. Nature, 2000, 407 (6806): 908-913.
10Tschp M, Weyer C, Tataranni P A, et al. Circulating ghrelin levels are de- creased in human obesity [J]. Diabetes, 2001,50 (4) : 707 -709.
