异基因造血干细胞移植治疗重型再生障碍性贫血71例临床分析
被引量:5
Clinical analysis of allogeneic hematopoietic stem cell transplantation for treatment of 71 cases of severe aplastic anemia
摘要
异基因造血干细胞移植(allo-HSCT)是目前治疗重型再生障碍性贫血(SAA)的重要手段。为了探讨allo—HSCT治疗SAA的临床疗效及预后影响因素,我们回顾性分析了71例接受allo—HSCT的SAA患者,现报告如下。
出处
《中华血液学杂志》
CAS
CSCD
北大核心
2016年第2期151-153,共3页
Chinese Journal of Hematology
参考文献11
-
1FouillardL, LabopinM, GratwohlA, et al. Outcome of 5651 hematopoietic stem cell transplants for hematological malignancies carried out in Europe in 1993: a reliability study of the registry[J]. Bone Marrow Transplant,2002,30(10):637-643.
-
2PasswegJR, PérezWS, EapenM, et al. Bone marrow trans-plants from mismatched related and unrelated donors for severe aplastic anemia[J]. Bone Marrow Transplant,2006,37(7):641-649.
-
3ScheinbergP, WuCO, NunezO, et al. Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine[J]. J Pediatr,2008,153(6):814-819. doi:10.1016/j.jpeds.2008.06.004.
-
4PasswegJR, MarshJC. Aplastic anemia: first-line treatment by immunosuppression and sibling marrow transplantation[J]. Hematology Am Soc Hematol Educ Program,2010,2010:36-42. doi:10.1182/asheducation-2010.1.36.
-
5KobayashiR, YabeH, HaraJ, et al. Preceding immunosuppressive therapy with antithymocyte globulin and ciclosporin increases the incidence of graft rejection in children with aplastic anaemia who underwent allogeneic bone marrow transplantation from HLA-identical siblings[J]. Br J Haematol,2006,135(5):693-696.
-
6AdesL, MaryJY, RobinM, et al. Long-term outcome after bone marrow transplantation for severe aplastic anemia[J]. Blood,2004,103(7):2490-2497.
-
7ChenJ, LeeV, LuoCJ, et al. Allogeneic stem cell transplantation for children with acquired severe aplastic anaemia: a retrospective study by the Viva-Asia Blood and Marrow Transplantation Group[J]. Br J Haematol,2013,162(3):383-391. doi:10.1111/bjh.12405.
-
8陈欣,魏嘉璘,黄勇,何炜,杨栋林,姜尔烈,马巧玲,周卢琨,林小婷,申昱妍,冯四洲,韩明哲.HLA匹配同胞供者异基因造血干细胞移植治疗重型再生障碍性贫血41例疗效分析[J].中华血液学杂志,2012,33(8):610-614. 被引量:11
-
9陈欣,魏嘉璘,黄勇,何祎,杨栋林,姜尔烈,马巧玲,姚剑峰,周卢琨,林小婷,申昱妍,杨欣,王钊,冯四洲,韩明哲.替代供者异基因造血干细胞移植治疗重型再生障碍性贫血19例疗效分析[J].中华血液学杂志,2014,35(1):9-12. 被引量:12
-
10StorbR, BlumeKG, O'DonnellMR, et al. Cyclophosphamide and antithymocyte globulin to condition patients with aplastic anemia for allogeneic marrow transplantations: the experience in four centers[J]. Biol Blood Marrow Transplant,2001,7(1):39-44.
二级参考文献27
-
1何祎,冯四洲,王玫,魏嘉璘,秦铁军,周征,翟文静,邱录贵,韩明哲.HLA相合同胞异基因造血干细胞移植治疗慢性粒细胞白血病第1次慢性期51例分析[J].中华血液学杂志,2005,26(7):389-392. 被引量:15
-
2Passweg JR, Marsh JC. Aplastic anemia: first-line treatment by immuno suppression and sibling marrow transplantation. Hematology Am Soc Hematol Educ Program,2010,36-42.
-
3Locasciulli A, Oneto R, Bacigalupo A, et al. Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppressive treatment in the last decade : a report from the European Group for Blood and Marrow Transplantation (EBMT). Haematologica, 2007, 92 : 11-18.
-
4Sangiolo D, Storb R, Deeg H J, et al. Outcome of allogeneic hematopoietic cell transplantation from HLA-identical siblings for severe aplastic anemia in patients over 40 years of age. Biol Blood Marrow Transplant, 2010, 16 : 1411-1418.
-
5Maury S, Bacigalupo A, Anderlini P, et al. Improved outcome of patients older than 30 years receiving HLA-identical sibling hematopoietic stem cell transplantation for severe acquired aplastic anemia using fludarabine-based conditioning: a comparison with conventional conditioning regimen. Haematologica, 2009, 94 : 1312- 1315.
-
6Kim H, Lee KH, Yoon SS, et al. Allogeneic hematopoietic stem cell transplant for adults over 40 years old with acquired aplastic anemia. Biol Blood Marrow Transplant,2012,1. doi: 10. 1016/j. bbmt. 2012.03.015.
-
7Chu R, Brazauskas R, Kan F, et al. Comparison of outcomes after transplantation of G-CSF-stimulated bone marrow grafts versus bone marrow or peripheral blood grafts from HLA-matched sibling donors for patients with severe aplastic anemia. Biol Blood Marrow Transplant, 2011, 17 : 1018-1024.
-
8Bacigalupo A, Socie' G, Schrezenmeier H, et al. Bone marrow versus peripheral blood sibling transplants in acquired aplastic anemia: survival advantage for marrow in all age groups. Haematologica,2012,7. DOI : 10. 3324/haematol. 2011. 054841.
-
9Jaime-Perez JC, Ruiz-Arguelles GJ, Gomez-Almaguer D. Haematopoietic stem cell transplantation to treat aplastic anaemia. Expert Opin Biol Ther, 2005, 5:617-626.
-
10Passweg J R, Perez WS, Eapen M, et al. Bone marrow transplants from mismatched related and unrelated donors for severe aplastic anemia. Bone Marrow Transplant ,2006,37:641-649.
共引文献21
-
1王旖婷,莫武宁.造血干细胞移植治疗常见血液病的研究进展[J].世界最新医学信息文摘,2020(89):35-38. 被引量:1
-
2刘天峰,竺晓凡.异基因造血干细胞移植治疗儿童获得性重型再生障碍性贫血研究进展[J].中华儿科杂志,2013,51(5):345-348. 被引量:1
-
3陈欣,魏嘉璘,黄勇,何祎,杨栋林,姜尔烈,马巧玲,姚剑峰,周卢琨,林小婷,申昱妍,杨欣,王钊,冯四洲,韩明哲.替代供者异基因造血干细胞移植治疗重型再生障碍性贫血19例疗效分析[J].中华血液学杂志,2014,35(1):9-12. 被引量:12
-
4及月茹,李国辉,刘强,陈任安,秦炜炜,刘利.抗人胸腺细胞免疫球蛋白/抗淋巴细胞免疫球蛋白联合环孢素A与异基因造血干细胞移植治疗再生障碍性贫血的疗效比较[J].国际输血及血液学杂志,2018,41(6):466-472. 被引量:9
-
5吴东升,丁茜,王前.祛铁治疗对再生障碍性贫血患者造血恢复的作用[J].牡丹江医学院学报,2014,35(4):58-59. 被引量:3
-
6王璐,韩冰.再生障碍性贫血的治疗进展[J].临床荟萃,2014,29(10):1083-1086. 被引量:11
-
7崔晓聪,王倩,高峰.异基因造血干细胞移植术后中枢神经系统真菌感染三例并文献复习[J].中华移植杂志(电子版),2014,8(3):40-43.
-
8王友君,李栋梁.脐带间充质干细胞对人类白细胞抗原不全相合造血干细胞移植治疗重型再生障碍性贫血效果的影响[J].临床误诊误治,2015,28(3):85-89. 被引量:7
-
9董志华,阚庆龄.探讨以大剂量环磷酰胺(HDCTX)治疗重型再生障碍性贫血(SAA)的可行性[J].中国医药指南,2015,13(9):84-85. 被引量:3
-
10聂大年,张伟明,李益清,尹松梅,马丽萍,谢双锋,王秀菊,吴裕丹,肖洁,刘红云,王婕妤,范美婷.异基因外周血干细胞移植治疗重型再生障碍性贫血16例疗效分析[J].广东医学,2015,36(7):1093-1095. 被引量:1
同被引文献42
-
1MarshJC, BallSE, CavenaghJ, et al. Guidelines for the diagnosis and management of aplastic anaemia [J]. Br J Haematol, 2009, 147(1):43–70. doi: 10.1111/j.1365-2141.2009. 07842.x.
-
2YagasakiH, TakahashiY, HamaA, et al. Comparison of matched-sibling donor BMT and unrelated donor BMT in children and adolescent with acquired severe aplastic anemia[J]. Bone Marrow Transplant, 2010, 45 (10):1508–1513. doi: 10.1038/bmt.2009.378.
-
3LeBK, SamuelssonH, GustafssonB, et al. Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells [J]. Leukemia, 2007, 21 (8):1733–1738. doi: 10.1038/sj.leu.2404777.
-
4SillaL, ValimV, AmorinB, et al. A safety and feasibility study with platelet lysate expanded bone marrow mesenchymal stromal cells for the treatment of acute graft-versus-host disease in Brazil [J]. Leuk Lymphoma, 2014, 55 (5):1203–1205. doi: 10.3109/10428194.2013.823495.
-
5HorwitzEM, MaziarzRT, KebriaeiP. MSCs in hematopoietic cell transplantation [J]. Biol Blood Marrow Transplant, 2011, 17 (1Suppl): S21–S29. doi: 10.1016/j.bbmt.2010.11.026.
-
6WangH, WangZ, ZhengX, et al. Hematopoietic stem cell transplantation with umbilical cord multipotent stromal cell infusion for the treatment of aplastic anemia--a single-center experience [J]. Cytotherapy, 2013, 15 (9):1118–1125. doi: 10. 1016/j.jcyt.2013.04.007.
-
7DufourC, PillonM, SocièG, et al. Outcome of aplastic anaemia in children. A study by the severe aplastic anaemia and paediatric disease working parties of the European group blood and bone marrow transplant [J]. Br J Haematol, 2015, 169(4):565–573. doi: 10.1111/bjh.13297.
-
8KimEJ, KimN, ChoSG. The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation [J]. Exp Mol Med, 2013, 45:e2. doi: 10.1038/emm.2013.2.
-
9DufourC, VeysP, CarraroE, et al. Similar outcome of upfront-unrelated and matched sibling stem cell transplantation in idiopathic paediatric aplastic anaemia. A study on behalf of the UK Paediatric BMT Working Party, Paediatric Diseases Working Party and Severe Aplastic Anaemia Working Party of EBMT [J]. Br J Haematol, 2015, 171 (4):585–594. doi: 10.1111/bjh.13614.
-
10ChungNG, LeeJW, JangPS, et al. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia [J]. Pediatr Transplant, 2013, 17 (4):387–393. doi: 10.1111/petr.12073.
引证文献5
-
1王玲,王恒湘,朱玲,郑晓丽,王志东,闫洪敏,丁丽,韩冬梅.HLA相合无关供者造血干细胞移植联合脐带间充质干细胞输注治疗儿童重型再生障碍性贫血19例疗效及安全性研究[J].中华血液学杂志,2016,37(6):453-457. 被引量:10
-
2周健,张龚莉,符粤文,朱兴虎,梁利杰,祖璎玲,王倩,喻凤宽,韩利杰,房佰俊,魏旭东,宋永平.异基因造血干细胞移植治疗41例重型再生障碍性贫血疗效分析[J].中华血液学杂志,2016,37(8):661-665. 被引量:5
-
3杨世伟,马荣军,赵娟娟,钟华芳,袁晓莉,姜丽,杨靖,雷平冲,张茵,符粤文,万鼎铭,朱尊民.不同方式异基因造血干细胞移植一线治疗儿童及青少年重型再生障碍性贫血的比较[J].中华血液学杂志,2018,39(3):184-189. 被引量:8
-
4罗成娟,陈静,王坚敏,覃霞,张冰花,朱华,王希楠,蔡娇阳,罗长缨.替代供者移植治疗儿童获得性再生障碍性贫血109例:单中心回顾性分析[J].中华血液学杂志,2020,41(2):128-131. 被引量:4
-
5王颖,王福旭,马夫天,温树鹏,牛志云,张学军.HLA全相合供者与亲缘单倍体供者异基因造血干细胞移植治疗输血依赖的非重型再生障碍性贫血效果比较[J].河北医科大学学报,2021,42(7):779-783. 被引量:1
二级引证文献26
-
1周健,韩利杰,祖璎玲,张龚莉,喻凤宽,符粤文,王倩,梁利杰,周虎,房佰俊,魏旭东,宋永平.重型再生障碍性贫血异基因造血干细胞移植后EBV相关淋巴细胞增殖性疾病五例报告及文献复习[J].中华血液学杂志,2016,37(11):998-1000. 被引量:1
-
2苏帜.造血生长因子治疗再生障碍性贫血合并肺部感染的疗效及对T淋巴细胞亚群的影响[J].医学新知,2016,26(6):423-425. 被引量:1
-
3唐红玲.慢性再生障碍性贫血的临床护理心得及方法探析[J].中国继续医学教育,2017,9(5):257-258. 被引量:3
-
4许兰平,黄晓军.我如何治疗造血干细胞移植后急性移植物抗宿主病[J].中华血液学杂志,2017,38(8):649-655. 被引量:7
-
5汪杰,李宏增,杨璐,赵待第,郭俊.自体分选造血干细胞移植治疗神经系统变性疾病的可行性分析[J].神经损伤与功能重建,2017,12(6):561-562.
-
6乔淑敏,王易,宋秀玲,岳屹囡.脐带间充质干细胞在造血干细胞移植中作用的研究进展[J].中国实验血液学杂志,2017,25(6):1847-1850. 被引量:2
-
7赵鸣悦,符粤文,王倩,艾昊,王勇奇,李婷婷,周健,房佰俊,魏旭东,宋永平.无关供者外周血干细胞联合脐血间充质干细胞共移植治疗难治性重型再生障碍性贫血Ⅱ型的疗效及安全性[J].中华内科杂志,2019,58(11):819-822. 被引量:5
-
8王涛,马梁明,朱秋娟,贡蓉,高志林,田卫伟.异基因造血干细胞移植治疗合并感染重型再生障碍性贫血36例临床分析[J].中华血液学杂志,2019,40(11):959-961. 被引量:6
-
9季艳萍,孙自敏.重型再生障碍性贫血治疗进展[J].器官移植,2020,11(2):293-297. 被引量:14
-
10魏元凤,黄东平.造血干细胞移植治疗再生障碍性贫血的现状[J].中国组织工程研究,2020,24(19):3093-3100. 被引量:7
-
1韩静敏,段金霞.分析异基因造血干细胞移植治疗重型再生障碍性贫血的护理要点[J].临床医药文献电子杂志,2015,2(27):5676-5677. 被引量:2
-
2梁娟,潘丽雅.重型再生障碍性贫血并发感染的观察与护理要点分析[J].人人健康,2016,0(2):165-165. 被引量:2
-
3徐晓敏,张琳敏,支芸.优质护理在重型再生障碍性贫血合并感染患者中的应用[J].医疗装备,2016,29(18):164-165. 被引量:6
-
4曹海琴.再生障碍性贫血的护理和治疗原则[J].世界最新医学信息文摘,2016,0(29):236-237.
-
5牛敏娟.护理干预对ICU患者焦虑和抑郁影响的研究[J].大家健康(学术版),2014(19):55-55. 被引量:1
-
6刘淑霞.重型再生障碍性贫血应用免疫抑制剂治疗期病人的护理[J].实用护理杂志,2000,16(7):9-10. 被引量:7
-
7陈小丽,张曦,孔佩艳,何刚,杜欣,孙爱华.HLA全相合异基因造血干细胞移植治疗骨髓纤维化患者的护理体会[J].当代护士(下旬刊),2014,21(4):85-86. 被引量:1
-
8郭广兰,刘湘林,王俊娟.异基因造血干细胞移植中真菌感染的预防和护理体会[J].成都军区医院学报,2003,5(2):62-63.
-
9王伯秋.干细胞移植治疗帕金森病[J].国外医学情报,2002,23(5):28-29.
-
10达万明.造血干细胞移植的最新进展[J].中国实用内科杂志,2000,20(1):41-43. 被引量:27