肝硬化合并消化道出血患者的临床影响因素分析

Clinical impact factors analysis of patients with hepatocirrhosis complicated with digestive tract bleeding

目的分析肝硬化合并消化道出血患者的危险因素。方法收集大连市第六人民医院2014年1月~2015年6月165例肝硬化患者的临床资料。按照是否发生消化道出血分为两组,分析两组患者的基线资料、实验室检查结果、临床指标等资料,并用单因素和多因素Logistic回归分析肝硬化合并消化道出血患者的危险因素。结果通过单因素及Logistic回归分析得出合并高血压、血小板计数降低、凝血酶原时间增加、脾脏增大、有腹水、白蛋白〈25 g/L、食管胃底静脉曲张是肝硬化合并消化道出血的高危因素。结论肝硬化患者应注意合并高血压、血小板计数降低、凝血酶原时间增加、脾脏增大、有腹水、白蛋白〈25 g/L、食管胃底静脉曲张等危险因素,通过对以上指标的控制可以预防消化道出血。

Objective To analyze the risk factors of patients with hepatocirrhosis complicated with digestive tract bleeding. Methods Clinical data of 165 patients with hepatocirrhosis from January 2014 to July 2015 in the Sixth People′s Hospital of Dalian City were selected.Patients were divided into two groups according to whether the digestive tract hemorrhage or not.The baseline information,laboratory examination results and clinical index of patients in two groups was analyzed respectively.The risk factors of patients with hepatocirrhosis complicated with digestive tract bleeding were analyzed by single factor and multi-factor Logistic regression analysis. Results It was founded from single factor and Logistic regression analysis that all of combined with hypertensive,low platelet count,prothrombin time increased,splenomegaly,seroperitoneum,albumin less than 25 g/L and esophageal and esophageal gastric varices was high risk factors of hepatocirrhosis complicated with digestive tract bleeding. Conclusion Hepatocirrhosis patients should pay attention to the risk factors of combined with hypertensive,low platelet count,prothrombin time increased,splenomegaly,seroperitoneum,albumin less than 25 g/L and esophageal and esophageal gastric varices Then digestive tract bleeding can be prevented by controlling the above-mentioned indexes.