摘要
目的比较MEBO湿润烧伤膏与红霉素眼膏治疗甲床裸露伤的临床疗效。方法采用随机单盲对比法将302例甲床裸露伤患者分为治疗组(152例)和对照组(150例)。治疗组采用MEBO湿润烧伤膏换药,对照组采用常规红霉素眼膏换药。治疗20天后比较两组患者创面的愈合时间、抗感染能力、局部治疗反应、药物止痛效果及毒副作用。结果两组患者创面均自然愈合,两组间年龄、性别、愈合面积及瘢痕发生率无差异,无统计学意义(P>0.05)。但MEBO湿润烧伤膏在缩短愈合时间(平均为11.25天)、良好的止痛效果(67.7%)及抗感染能力(2=33.18)优于红霉素眼膏,差异有显著的统计学意义(P<0.001)。而且价格便宜,药物毒副作用少,患者耐受性好。结论湿润烧伤膏是一种效果显著的治疗甲床裸露伤的首选外用药。
Objective To observe the clinical results of MEBO and erythromycin ointment in treatment of exposed nail bed injury. Methods 302 exposed nail bed injury patients were divided into treatment group （152 cases） and control group （150 cases）. The treatment group was treated with MEBO dressing and control group with conventional erythro- mycin ointment dressing. The healing time, resistance to infection, topical treatment response, analgesic effect and side effects of drugs were observed. Results The wounds of the two groups were all heal in natural ways. The age, gender, healing area and scar incidence was not different between the two groups （P〉0. 05）. The healing time, good analgesic effect and resistance to infection of treatment group were superior to control group （P〈0. 001）. Compared with the con- trol group, treatment group was cheap, had less drug side effects and toleration. MEBO has significant effect in treat- ment of exposed nail bed injury.
出处
《西部医学》
2016年第2期282-284,共3页
Medical Journal of West China
基金
国家自然科学基金(81301568)
关键词
红霉素眼膏
甲床裸露伤
MEBO
Erythromyein ointment
Exposed nail bed injury
