期刊文献+

僵人综合征误诊临床分析 被引量:1

Clinical Analysis of Misdiagnosis of Stiff Person Syndrome
下载PDF
导出
摘要 目的探讨僵人综合征的临床特点,分析误诊原因,以减少误诊误治。方法对我院收治的曾误诊的2例僵人综合征的临床资料进行回顾性分析。结果本文2例均因肢体强直就诊,曾分别误诊为帕金森病和癔症,均按误诊疾病给予相应治疗效果不佳。入我院后经肌电图及脑脊液等检查皆确诊为僵人综合征,给予氯硝西泮及地西泮等药物治疗后均症状好转出院。随访6个月和1年,无复发。结论僵人综合征是临床罕见的肌肉疾病,临床表现缺乏特异性及对认识不足是导致误诊误治的主要原因。 Objective To investigate the clinical characteristics of stiff person syndrome,analyze the causes of misdiagnosis in order to reduce misdiagnosis rate. Methods The clinical data of 2 misdiagnosed cases of stiff person syndrome were analyzed retrospectively. Results Both the two patients were admitted for limb stiffness,and were misdiagnosed as Parkinson's disease and hysteria respectively. Both underwent treatment with poor effect. Upon admission,they took ENG,cerebrospinal fluid and other tests,after which they were confirmed with stiff-man syndrome. After Clonazepam and Diazepam and other medications,the symptoms improved and were discharged after treatment. Follow-up of 6 months and 1 year showed no recurrence. Conclusion Stiff person syndrome is a clinically rare muscle disease. The main cause of misdiagnosis is due to the lack of specific clinical manifestations and lack of knowledge.
出处 《临床误诊误治》 2016年第2期47-49,共3页 Clinical Misdiagnosis & Mistherapy
关键词 僵人综合征 误诊 帕金森病 癔症 Stiff-person syndrome Misdiagnosis Parkinson disease Hysteria
  • 相关文献

参考文献16

二级参考文献77

  • 1沈沸,钱可久.僵人综合征[J].神经病学与神经康复学杂志,2005,2(1):59-65. 被引量:2
  • 2汤晓芙.僵人综合征(讲座)[J].中国神经免疫学和神经病学杂志,2004,11(3):171-173. 被引量:12
  • 3石强,黄旭升,田成林,于生元,管维平,吴卫平,蒲传强.僵人综合征的临床及电生理特点[J].中华神经医学杂志,2005,4(7):720-722. 被引量:3
  • 4郭秀海,王玉平,贾建平,张雁华,李宁,李存江,董会卿,吴卫平.僵人综合征及僵人叠加综合征六例的临床特点及丙种球蛋白疗效观察[J].中华神经科杂志,2006,39(4):246-249. 被引量:22
  • 5许贤豪.僵人综合征[A].见:许贤豪.神经免疫学:第1版[C].武汉:湖北科学技术出版社,2000.176-183.
  • 6Duddy ME, Baker MR. Stiff person syndrome. Front Neurol Neurosci, 2009. 26: 147-165.
  • 7Maddison P. Neuromyotonia. Clin Neurophysiol, 2006, 117: 2115-2127.
  • 8Fukushima K, Sato T, Mitsuhashi S, et al. Isaacs' syndrome associated with myasthenia gravis, showing remission after cytoreductive surgery of pleural recurrence of thymoma. Neuromuscul Disord, 2006, 16: 763-765.
  • 9Aso Y, Sato A, Narimatsu M, et al. Stiff-man syndrome associated with antecedent myasthenia gravis and organ-specific autoimmunopathy. Intern Med, 1997, 36: 308-311.
  • 10Skeie GO ,Romi F. Paraneoplastic myasthenia gravis :immunological and clinical aspects. Eur J Neurol, 2008, 15: 1029-1033.

共引文献16

同被引文献3

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部