耳穴埋豆配合安神方治疗帕金森病失眠(肝肾阴虚型)疗效观察

Efficacy Observation on Treating Parkinson's Disease with Insomnia(Liver and Kidney Yin Deficiency Syndrome)with Anshen Decoction Plus Pressing Ear Acupoint with Bean

目的:观察耳穴埋豆配合安神方治疗帕金森病失眠(肝肾阴虚型)的临床疗效、安全性。方法:研究设计采用随机对照研究设计,研究对象为58例帕金森病失眠(肝肾阴虚型)患者,随机分成治疗组29例和对照组29例,对照组予帕金森病常规治疗,并予阿普唑仑片每晚0.4 mg,治疗组在对照组的基础上,加耳穴埋豆配合安神方治疗,观察4周,比较2组治疗前后的PSQI评分以及其安全性、依从性。结果:治疗组治疗前后的PSQI总分分别为(12.55±2.11)分和(5.92±2.86)分,对照组治疗前后的PSQI总分分别为(12.43±2.17)分和(8.28±2.56)分,两组治疗后均有明显地改善(P<0.05),而且两组治疗后的PSQI总分组间比较差异有统计学意义(P<0.05)。结论:耳穴埋豆配合安神方治疗帕金森病失眠(肝肾阴虚型)有显著疗效,且安全性高。

Objective：To observe clinical efficacy and safety on treating Parkinson＇s disease with insomnia（liver and kidney Yin deficiency syndrome）with Anshen Decoction plus pressing ear acupoint with bean. Methods：Study design using randomized controlled study design,the research object of 58 cases of Parkinson＇s disease with insomnia（liver and kidney Yin deficiency syndrome）,randomly divided into the treatment group 29 cases and control group 29 cases.The control group with conventional treatment of Parkinson＇s disease,and alprazolam tablets 0.4 mg per night,and the treatment group on the basis of the control group,with Anshen Decoction plus pressing ear acupoint with bean,observation of 4 weeks,compare the two groups before and after treatment of PSQI score and its security and compliance. Results：The treatment group before and after treatment of PSQI scores respectively（12.55±2.11）and（5.92±2.86）and control group before and after treatment of PSQI scores respectively（12.43±2.17）and（8.28±2.56）,the two groups are significantly improved after treatment（P0.05）,and the two groups after treatment of PSQI overall comparative differences between groups was statistically significant（P0.05）. Conclusion：Treating Parkinson＇s disease with insomnia（liver and kidney Yin deficiency syndrome）with Anshen Decoction plus pressing ear acupoint with bean have significant curative effect,and high safety.