补脾祛瘀法对直肠绒毛管状腺瘤术后患者临床疗效影响

Clinical Curative Effect of Tonifying Spleen and Removing Blood Stasis on Postoperative Patients with Rectal Tubulovillous Adenoma

目的:探究补脾祛瘀法对直肠绒毛管状腺瘤术后患者临床疗效的影响。方法:选取我院收治的直肠绒毛管状腺瘤术后患者80例,采用随机数字表随机分为两组,每组各40例,其中对照组在给予顺铂注射液治疗,实验组在对照组的基础上给予补脾祛瘀法治疗。两组均以1个月为1个疗程,治疗2个疗程。治疗结束后,检测临床总有效率及术后尿潴留、发热、直肠瘘等并发症的出现率,并在出院后随访12个月,对比两组患者的癌变率。结果:(1)经治疗后,两组术后患者的症状均有好转,实验组患者治疗后的总有效率为90.0%,对照组患者治疗后的总有效率为80.0%,实验组总有效率略高于对照组,两组结果有显著性差异,有统计学意义(P<0.05)。(2)经治疗后,仅有少部分患者出现并发症,其中实验组并发症出现率为12.5%,对照并发症的出现率为25.0%,实验组患者并发症的出现率明显低于对照组,两组结果有显著性差异,有统计学意义(P<0.05)。(3)出院后随访12个月,可发现部分患者有癌变倾向,其中实验组的癌变率为7.5%,对照组的癌变率为17.5%,实验组癌变率明显低于对照组,两组结果有显著性差异,有统计学意义(P<0.05)。结论:手术是直肠绒毛管状腺瘤的主要治疗手段,在术后配合使用补脾祛瘀为主的中药汤剂,能够有效改善各临床症状,降低抑制腺瘤药的毒副作用,减少并发症的发生率及腺瘤的癌变率,并对临床具有指导意义,值得临床推广。

Objective：To explore the clinical curative effect that the tonifying spleen and dispelling stasis method in patients with rectal villus tubular adenoma postoperative. Methods：Select 80 rectal villus tubular adenoma patients,divided into two groups randomly（40 patients per group）. The control group treated with cisplatin injection,the other group on the basis of tonifying spleen and dispelling stasis method was given. Two groups in a month for a period of treatment,after 2 courses of treatment,compared the clinical results,included the incidence of postoperative urinary retention,fever,rectal fistula and other complications,and 12 months after discharge,compared with the two groups of patients with cancer rate.Results：（1）After treatment,two groups of patients with postoperative symptoms were improved,after treatment the experimental group patients＇ total effective rate was 90.0%,the control group＇s effective rate was 80.0%,the experimental group slightly higher than the control group,there were significant differences between the two groups,with statistical significance（P0.05）.（2）After treatment,only a small number of cancer complications,including experimental complications rate was 12.5%,against the emergence of the complication rate was 25.0%,the experimental group patients with the emergence of the complication rate lower than the control group,the two groups have significant difference,there is statistical significance（P0.05）.（3）After 12 months of follow-up,can be found in some patients with malignant tendency,the cancer rate of the experimental group was 7.5%,the control group was 17.5%,the incidence rate of the experimental group was significantly lower than that of the control group,there were significant differences between the two groups,there was a significant difference between the two groups. Statistical significance（P0.05）. Conclusion：Surgery is the main treatment of rectal villus tubular adenoma,mainly used in postoperative tonifying spleen and dispelling stasis soup of traditional Chinese medicine agent,can effectively improve the clinical symptoms,reduce the side effects of inhibition of adenoma medicine,reduce the incidence of complications and adenoma canceration rate,on clinical has the means guide significance,it is worth clinical promotion.