摘要
目的探讨非小细胞肺癌恶性胸腔积液患者存活率的影响因素。方法回顾性分析199例非小细胞肺癌恶性胸腔积液患者的临床资料,将患者年龄、性别、吸烟史、转移位点、病理形态、乳酸脱氢酶、血小板、血清C反应蛋白、顺铂胸腔内灌注这9个因素作为研究对象,采用COX多因素回归分析NSCLC恶性胸腔积液存活率的独立影响因子。结果单因素分析显示病理形态、乳酸脱氢酶、血清C反应蛋白、顺铂胸腔内灌注是患者预后影响因素,COX多因素回归分析显示血清C反应蛋白和顺铂胸腔内灌注为预后独立的影响因子。结论血清反应蛋白和顺铂胸腔内灌注为预后独立的影响因子。
Objective To investigate the factors affecting survival in non-small cell lung cancer（ NSCLC） patients with malignant pleural effusion. Methods The clinical data of 199 cases of NSCLC patients with malignant pleural effusion were retrospectively analyzed. Age,gender,smoking status,metastatic sites,histopathological type,LDH,platelets,CRP,cisplatin intrathoracic perfusion were analyzed,and COX regression analysis was used to analyze the influence factors of NSCLC patients with malignant pleural effusions. Results Single factor analysis showed that pathological morphology,lactate dehydrogenase,serum CRP,and cisplatin in patients with pleural perfusion were prognostic factors,and COX regression analysis showed that CRP,cisplatin intrathoracic perfusion were independent prognostic factors. Conclusion CRP and cisplatin intrathoracic perfusion are independent prognostic factors.
出处
《实用癌症杂志》
2016年第2期246-248,共3页
The Practical Journal of Cancer
关键词
预后因素
非小细胞肺癌
恶性胸腔积液
Prognostic factor
Non-small cell lung cancer（NSCLC）
Malignant pleural effusions
