极低出生体重儿胃液pH值与喂养不耐受的相关性研究

Relationship of Gastric pH Value and Feeding Intolerance in Very Low Birth Weight Infants （VLB-WI）

【目的】探讨极低出生体重儿（VLBwI）胃液pH值与喂养不耐受的关系。【方法】选取2010年1月至2014年12月本院新生儿重症监护室（NICu）收治的VLBWI80例。参照喂养不耐受诊断标准，将入选患几分为喂养耐受组36例，喂养不耐受组44例。比较两组患儿的胃液pH值、喂养耐受情况（胃残留量、腹胀、呕吐、大便异常）。【结果】喂养不耐受组喂养不耐受发生率为100％，高于喂养耐受组的8．33％（P〈0．05），同时其平均胃液pH值高于喂养不耐受组（P〈0．05）；VLBWI胃液pH值与胃残留量呈正相关，r=0．77，P=0．00。【结论】VLBwI胃液pH值与喂养不耐受存在显著相关，对VLBWI胃液pH值的有效监控能帮助临床医生及护士监测新生儿胃肠功能，为促进新生儿疾病康复提供参考。

[Objective]To explore the relationship of gastric pH value and feeding intolerance in very low birth weight infant （VLBWI）.[Method] 80 cases of very low birth weight children in our hospital from January 2010 to December 2014 also in the neonatal intensive care unit were chosen for our study. Using the feeding intolerance diagnostic criteria, the children were selected and divided into two groups. Group 1 had no feeding intolerance （36 cases） and Group 2 had feeding in tolerance （44 cases）. The two groups of children were observed in respect to gastric pH value, feeding conditions （feeding time, the amount of intake and gastric residue）, and feeding tolerance （bloating times, frequency of vomiting, abnormal stool frequency）.[Results]Group 1 had a feeding intolerance rate of 100%, significantly higher than the 8.33% rate in Group 2 （ P 〈0.05）, while the average gastric pH value was also higher in Group 1 than Group 2 （ P 〈0.05）. The occurrence of VLBWI feeding intolerance and gas- tric pH value were positively correlated r = 0.77, P = 0.00.[Conclusion]Gastric pH value in very low weight newborns with feeding intolerance showed significant correlation with the gastric pH levels in the infants. It is worthy of effective monitoring to help clinicians and nurses to understand neonatal gastrointestinal function and promote neonatal rehabilitation reference.