预防老年性白内障术中虹膜松弛综合征的研究

The study of preventing floppy iris syndrome during age-related cataract surgery

目的探讨术前应用阿托品及新福林滴眼对高危人群在老年性白内障术中出现虹膜松弛综合征的预防作用。方法回顾性分析我院2012年1月至2013年12月施行的老年性白内障手术596例（641眼）。对手术患者术前询问全身病史和用药史，2013年对有良性前列腺增生症并服用坦洛新或非那雄胺的患者52眼术前应用阿托品及新福林滴眼，与2012年术前未用该药者对比术中虹膜松弛综合征的发生情况。结果2012年发病10眼，占2．95％；2013年为2眼，占0．66％，两组发生率差异有统计学意义（P〈0．05）。结论老年性白内障术中易出现虹膜松弛综合征的高危人群术前应用阿托品及新福林滴眼对术中出现虹膜松弛综合征有预防作用。

Objective To investigate the clinical effect of applying atropine and neosynephrine to prevent intraoperative floppy iris syndrome during age-related cataract surgery in high risk patients. Methods Six hundred and forty-one eyes of 596 patients receiving age-related cataract surgery in our hospital from Jan. 2012 to Dec. 2013 were analysed. The past history of illness and drug history before the surgery were enquired. 50 patients（52 eyes） that had benign prostatic hyperplasia in 2013 and used tamsulosin and finasteride were applied with atropine and neosynephrine. Patients of the same history in 2012 had not applied atropine or neosynephrine. The incidence of intraoperative floppy iris syndrome during surgery between patients in 2013 and 2012 were compared. Results The intraoperative floppy iris syndrome occurred in 10 eyes （ 2.95% ） in 2012 and 2 eyes （ 0.66% ） in 2013, the difference was statistically significant （P 〈 0.05 ）. Conclusion Atropine and neosynephrine can be applied in patients with high risk of intraoperative floppy iris syndrome, to prevent its occurance during age-related cataract surgery.