连续性肾脏替代治疗对重症急性肾衰竭患者血流动力学及肾功能的影响

Continuous renal replacement therapy for severe acute renal failure and renal function in patients with hemodynamic effects

目的探讨连续性肾脏替代治疗对重症急性肾衰竭患者血流动力学及肾功能的影响。方法选择42例重症急性肾衰竭患者为研究对象,分别采用连续性肾脏替代治疗(CRRT组,21例)和间歇性血液透析治疗(IHD组,21例)。观察两组血流动力学指标、肾功能及治疗效果。结果 1血流动力学参数:CRRT组肌酐、尿素氮明显低于IHD,KT/V值明显高于IHD组(P<0.05);2肾功能:CRRT组肌酐、尿素氮明显低于IHD组,KT/V值明显高于IHD组(P<0.05);3与IHD组比较,CRRT组APACHE-Ⅱ评分、尿量恢复600ml/d、低血压、心律失常等并发症明显低于IHD组(P<0.05)。结论连续性肾脏替代治疗能维持重症急性肾衰竭患者血流动力学稳定,改善肾功能,提高治疗效果,减少并发症。

Objective To investigate the effect of continuous renal replacement therapy for severe acute renal failure patients hemodynamics and renal function. Method Choose 42 cases of severe acute renal failure patients for research object,respectively,by continuous renal replacement therapy（ CRRT group,21 cases） and intermittent hemodialysis treatment（ IHD group,n = 21）. Observe two groups of hemodynamic parameters,renal function and treatment effect. Result 1 The hemodynamic parameters： CRRT group creatinine and urea nitrogen was significantly lower than that of IHD,KT / V value was significantly higher than that of IHD group（ P〈 0. 05）; 2Renal function： CRRT group creatinine and urea nitrogen was significantly lower than that of IHD,KT / V value was significantly higher than that of IHD group（ P 〈0. 05）; 3IHD group compared with CRRT group APACHE-Ⅱ score,urine volume recovery600 ml / d,hypotension,cardiac disorders and other complications was significantly lower than that of the IHD group（ P 〈0. 05）. Conclusion Continuous renal replacement therapy can maintain in critically ill patients with acute renal failure patients who are hemodynamically stable,improve renal function,improve the therapeutic effect,less complications.