正常踝关节软骨厚度的低场MRI测量研究

To Measure the Articular Cartilage Thickness Using 0.3T MRI in the Normal Ankle Joint

目的探讨低场MRI测量踝关节软骨厚度的可行性及软骨厚度与年龄、性别、体重、身高的相关性。方法选取左踝关节无外伤、无任何临床症状的健康自愿者160例,依据年龄分为8个组,每组20例,用SE-T1WI和WFT1WI序列行冠状位、矢状位扫描,每个踝关节选取5个测量点,测量厚度为关节软骨面至软骨下低信号。结果踝关节软骨厚度分布呈现非均匀性,外踝侧软骨平均厚度为1.82mm,顶前软骨1.84mm,顶中软骨1.82mm,顶后软骨1.81mm,顶前平均厚度大于顶后。男性软骨平均厚度大于女性,分别为(1.81±0.30)mm与(1.79±0.25)mm。15岁以前,身高<140cm,体重<45kg,踝关节软骨厚度与年龄、体重、身高呈负相关;15岁以后,身高>140cm,体重>45kg,软骨厚度与年龄、体重、身高无明显相关性。结论正常踝关节距骨软骨厚度分布呈非均匀性,男性软骨厚度大于女性,15岁以前踝关节软骨厚度与身高、体重、年龄呈负相关;15岁以后软骨厚度与三者无直线相关性。

Objective To investigate the feasibility of using lowfield magnetic resonance to measure the thickness of ankle joint cartilage, the relationship between the thickness of the cartilage and age, gender, weight and height were analyzed at the same time. Methods 160 healthy volunteers with normal left ankles were chosen and divided into 8 groups, and each group contains 20 volunteers according to their age. All normal ankles were scanned through sagittal and coronal plane with SE-T1 WI and WF-T1 WI sequences. We chose 5 measurement from the surface of the cartilage to the subchondral. Results The distribution of the thickness of cartilage is nonuniformity. The average thickness of cartilage measured from the lateral malleolus is 1.82 mm, and from the front, middle and rear were as follows： 1.84 mm 1.82 mm 1.81 mm, and the front in average is more than the rear. The average thickness in male is more in female,（1.81±0.30）mm and（1.79±0.25）mm respectively. The thickness of ankle joint was negatively related to age, weight and height before 15 years old if the height is less than 140 cm and the weight is less than 45 kg. However, there was no obvious relationship between them after 15 years old if the height is more than 140 cm and the height is more than 45 kg. Conclusion The distribution of the thickness of talar cartilage from normal ankle joint is nonuniformity. The thickness in male is more than in female, and it is negatively related to age, weight and height before 15 years old and there is no linear correlation after 15.