AMPK在动脉粥样硬化中的作用

The role of AMPK(AMP-activated protein kinase) in atherosclerosis

目的 AMPK(腺苷酸活化蛋白激酶)调节机体内合成代谢和分解代谢的主要蛋白激酶,不仅影响着蛋白质、糖原、脂肪酸三大代谢途径,在心血管受到刺激时通过影响细胞周期和抑制细胞增殖起到保护心血管的作用。动脉粥样硬化预防和治疗中,AMPK在促进胆固醇的流出、加速脂肪酸氧化和抑制炎症形成方面均有影响。

AMPK（AMP-activated protein kinase） regulate the body＇s anabolic and catabolic main protein kinase, it affects not only protein, glycogen, fatty acid metabolic pathway of three. n cardiovascular stimulation by influencing the cell cycle and protect cardiovascular inhibition of cell proliferation. Atherosclerosis prevention and treatment, AMPK have influence in promoting the outflow of cholesterol, accelerate the formation of fatty acid oxidation and inhibit inflammation.