柴胡疏肝散配合米氮平片治疗抑郁症临床观察

Clinical observation on treating depression with Chaihu Shugan San plus mirtazapine tablets

目的：观察柴胡疏肝散配合米氮平片治疗抑郁症的临床疗效。方法：将符合抑郁症诊断标准的60例患者随机分成治疗组和对照组,每组各30例,治疗组给予柴胡疏肝散配合米氮平片（15~45mg/d）。对照组单纯用米氮平片（15~45mg/d）,一个疗程为8周。结果：一个治疗为8周后,两组HAMD评分均较治疗前有明显下降,P〈0.05;治疗组有效率为90%,显效率为80%,对照组有效率为80%,显效率为60%,两组疗效比较,P〈0.05;两组治疗期间不良反应发生率比较,P〈0.05,差异具有统计学意义。结论：柴胡疏肝散配合米氮平治疗抑郁症疗效佳,不良反应少,值得大力推广。

Objective： To observe the clinical efficacy of Chaihu Shugan San plus mirtazapine tablets on depression. Methods： 60 patients were randomly divided into the treatment group and the control group; 30 cases in the treatment group were given Chaihu Shugan San plus mirtazapine tablets（15~45mg/d）. The control group was treated with mirtazapine tablets（15~45mg/d）, for 8 weeks. Results： In 8 weeks, in the two groups, HAMD scores were significantly decreased than before, P〈0.05; In the treatment group the efficiency was 90%, better than 80% in the control group, P〈0.05; In two groups the incidence of adverse reactions, during treatment, showed statistical significance, P〈0.05. Conclusion： Chaihu Shugan San with mirtazapine showed good efficacy on depression, with fewer adverse reactions, and is worthy of promoting.