摘要
目的:研究加味逍遥丸联合电针治疗抑郁症治疗效果、药物相关的不良反应及安全性。方法:95例患者随机分成两组,分别运用加味逍遥丸联合电针治疗和氟西汀治疗,疗程6周,在治疗前、治疗2周、4周、6周末采用汉密尔顿抑郁量表减分率评定治疗效果,观察不良反应。结果:治疗组组间比较:在治疗2周、4周、6周后T1分别为2.64、9.21、15.72,P<0.05、P<0.01、P<0.01,对照组组间比较:在治疗2周、4周、6周后,T2分别为:2.29、7.23、12.20,P<0.05、P<0.01、P<0.01,两组内比较均有统计学意义;而两组间相比:P>0.05,无统计学意义;治疗6周后治疗组显效率为67.4%,总有效率为84.8%,对照组显效率为65.9%,总有效率为81.8%,差异无统计学意义,P>0.05;两组不良反应比较无显著性差异,P>0.05。结论:加味逍遥丸配合电针治疗抑郁症具有安全有效,不良反应少而轻,安全性的特点,可以运用于抑郁症的治疗。
Objective: To study the efficacy and safety of modified Xiaoyao Pill combined with electro-acupuncture in the treatment of depression. Methods: 95 cases were randomly divided into two groups in which research group was treated with modified Xiaoyao Pill combined with electro-acupuncture and the control group took fluoxetine for 6 weeks. The effects were assessed with the Hamilton Depression Scale(HAMD), adverse reactions before treatment and at the ends of the 2nd,4th and 6th week were compared. Results: Comparison between treatment way : After 2 weeks,4 weeks,6 weeks,T1 was 2.64,9.21,15.72,P〈0.05,P〈0.01,P〈0.01. Comparison between control way after 2 weeks,4 weeks,6 weeks,T2 was 2.29,7.23,12.20,P〈0.05,P〈0.01,P〈0.01, the two groups had significant difference(P〉0.05).At the end of the 6th week, the significant effective rate was 67.39%,the total effective rate was 84.78%of the research group. The significant effective rate was 65.91%,the total effective rate was 81.82%of the control group. There was no significant difference(P〉0.05);There was no significant difference in adverse reactions(P〉0.05).Conclusion: Modified Xiaoyao Pill combined with electro-acupuncture is safe and effective in the treatment of depression with lower side effects.
出处
《中医临床研究》
2016年第3期26-27,共2页
Clinical Journal Of Chinese Medicine
关键词
加味逍遥丸
电针
氟西汀
抑郁症
Modified Xiaoyao Pill
Electro-acupuncture
Fluoxetine
Depression