常用活血化瘀中成药在预防过敏性紫癜患儿肾损害中的应用

The application of Chinese patent drug of promoting blood circulation for removing blood stasis in the prevention of renal injury of children with HSP

过敏性紫癜是儿童时期常见的一种全身性小血管变态反应性出血性血管炎综合征,临床主要表现为皮肤紫癜、腹痛、关节痛及肾损害等;其中肾损害是决定其预后的重要因素,且西医目前尚无特效的药物能够早期干预肾损害的进展。中医药治疗HSP有显著的疗效,尤其是活血化瘀药物在早期预防肾损害方面起着重要的作用。通过总结常用的活血化瘀药物,为临床治疗HSP、预防早期肾损害提供理论的依据。

Henoch-Schonlein Purpura（HSP）is a common systemic small vessel allergic hemorrhagic vasculitis syndrome in children, which manifests clinically in cutaneous purpura, abdominal pain, joint pain and renal injury, etc., of which the renal injury is a key factor in prognosis; there is still no effective western medicine which could function as an early intervention for the renal injury. TCM has a significant effect in treating HSP, especially Chinese patent drug of promoting blood circulation for removing blood stasis could prevent the renal injury in the early stage. It would provide theoretical basis for the clinical treatment of HSP and prevention of the renal injury by summarizing the frequently used drug of promoting blood circulation for removing blood stasis.