中西医结合治疗胃癌术后肠道功能紊乱的临床研究

Clinical study of combination of TCM and western medicine in treating intestinal dysfunction after gastric cancer operation

目的:观察肌内注射新斯的明、足三里穴位注射新斯的明治疗胃癌根治术后胃肠功能紊乱的临床研究。方法:将90例符合诊断标准的术后胃肠功能紊乱的患者随机分三组,每组30例,三组患者无显著差异。三组都术前胃镜取活检确诊,无手术禁忌证,手术方式为癌根治术,术后出现胃肠功能紊乱的症状,肌内注射组:给予肌内注射甲硫酸新斯的明0.5 mg。穴位注射组:选双侧足三里注入新斯的明0.5 mg。对照组:只给予基础治疗。结果:肌内注射组、穴位注射组和对照组比较患者的鸣音恢复、排气、排便时间均显著提前,而穴位组更显著;治疗组患者总有效率显著高于对照组而穴位组更显著。结论:足三里注射新斯的明较肌内注射新斯的明治疗胃癌术后肠道功能紊乱可以取得更好的疗效。

Objective： To observe the clinical effect of intramuscular injection of neostigmine, Zusanli acupoint injection of neostigminein in treating intestinal dysfunction after gastric cancer operation. Methods： 90 patients with intestinal dysfunction after gastric cancer operation who met the diagnostic criteria were randomly divided into 3 groups, with 30 cases in each group, 3 groups had no significant difference. All 3 groups were confirmed by preoperative gastroscopic biops, there was no operation contraindication, and radical resection of cancer was given, there was intestinal dysfunction after gastric cancer operation. The intramuscular injection group received an intramuscular injection of neostigmine methylsulfate 0.5 mg. Acupoint injection group received bilateral Zusanli injection of neostigmine 0.5 mg while the control group received only basic therapy. Results： Compared with that of patients in the control group, bowel sounds returning, wind-breaking and defecating time of patients in intramuscular injection group and acupoint injection group were significantly earlier, and those of acupoint injection group were more significantly earlier; total effective rate of the intramuscular injection group was significantly higher than that of the control group and that of the acupoint injection group was the most significant. Conclusion： Compared with intramuscular injection of neostigmine, Zusanli injection of neostigmine had get better curative effect in treating intestinal dysfunction after gastric cancer operation.