早期糖尿病肾病与糖尿病无肾损伤患者代谢指标的比较

Comparing the Metabolic Index of Patients With Early Diabetic Nephropathy and Diabetic With Kidney Damage

目的探讨早期糖尿病肾病和糖尿病无肾损伤患者的各项代谢指标差异性,为临床治疗提供可靠的依据。方法回顾88例2型糖尿病(T2 DM)患者的UMA、甘油三酯(TG)、胆固醇(TC)、高/低密度脂蛋白(HDL-C/LDL-C)、尿酸(UA)、糖化血红蛋白(Hb A 1 c)及入院时的年龄、病程与体重指数(BMI)、收缩压(SBP)、舒张压(DBP)、压差(PP),最后根据UMA水平分成两组(≤30μg/ml为正常组,30μg/ml^300μg/ml为DN组),对比两组患者的各项指标差异性。结果正常组和DN组患者的BMI、SBP、PP、HDL-C等指标有很大差异性,其他指标无明显的差异性。结论临床中需要对糖尿病肾病患者的体重、SBP、PP及HDL-C等指标进行有效控制,可延缓患者的肾损伤症状,改善症状和生存质量。

Objective To investigate the differences of metabolic indexes in patients with early diabetic nephropathy and diabetes without renal injury, and provide reliable evidence for clinical treatment. UMA patients Methods Review 88 cases of urinary protein was negative, creatinine（CR）, blood urea nitrogen（BUN） were in the normal range of type 2 diabetes mellitus（T 2 DM）, triglyceride（TG）, total cholesterol（TC）, high / low density lipoprotein（HDL-C/LDL-C）, uric acid（UA）, glycosylated hemoglobin（Hb A 1 c） and admission to the age, course of disease and body mass index（BMI）, systolic blood pressure（SBP） and diastolic blood pressure（DBP）, differential pressure（PP）, and finally according to the UMA level into two groups（less than or equal to 30 μg/ml for normal group, 30 μg/ml to 300 μg/ml for DN group, compared two groups of patients with the index difference. Results The BMI, SBP, PP, HDL-C and other indicators of the normal group and DN group were significantly different, other indicators had no significant difference. Conclusion The weight, SBP, PP, HDL-C and other indicators of diabetic nephropathy patients need to be effectively controlled, the renal injury symptoms can be delayed, improve the symptoms and quality of life of patients.