从“辨病论治”谈糖尿病前期胰岛素抵抗的核心病机

Discussion on the Core Pathogenesis of Prediabetes Insulin Resistance from "Treatment based on Disease Differentiation"

胰岛素抵抗是糖尿病前期机体普遍存在的病理状态,减轻胰岛素抵抗是降低糖尿病发病率的关键。根据中医"治未病"思想,对糖尿病前期进行干预,改善胰岛素敏感性,是预防糖尿病发生的有效方法。但目前治疗糖尿病前期的中药繁多,证型复杂,鲜少从"辨病论治"的角度进行探讨。文章结合目前糖尿病前期胰岛素抵抗的研究情况,总结其核心病机为脾气亏虚,痰浊内阻,治应以益气健脾化湿为主。

Insulin resistance is a common pathology in prediabetes, while mitigating insulin resistance is the key to reduce morbidity of diabetes. It is of highly significance to take early intervention in prediabetes employing the TCM principle of ＂ preventive treat-ment of disease＂. However, there are so many Chinese medicines and syndrome types, and has rare discussion from ＂ treatment based on disease differentiation＂. According to the research, we thought that the core pathogenesis of prediabetes insulin resistance is spleen deficiency and phlegm resistance, and treatment should be benefiting qi, invigorating spleen, and removing dampness.