军团菌感染诊断方法评析

Evaluation of the diagnostic methods for Legionella infection

军团菌感染的主要诊断方法包括分离培养法、尿抗原检测法、免疫学方法和核酸扩增法,每种检测方法各有利弊。由于军团菌分型复杂以及检测方法的局限性,军团菌感染处于被低估状态。军团菌感染常表现为重症,应积极进行多种方法检测以早期诊断、早期目标治疗,进而改善患者预后、降低病死率。

The diagnostic methods for LegioneUa infection include microbiological culture, urinary antigen test, immunological methods and nucleic acid amplification test. Each method has advantages and disadvantages. Due to the complicated species and serogroups of Legionella and the limitation of the diagnostic methods, Legionella infection is under-evaluated. The marnfestation of Leginella infection is usually severe. Diagnostic tests should be performed in order to make early diagnosis. Early target treatment might improve the patients＇ outcome and decrease the mortality of the disease.