骨髓纤维化的发病机制及临床表现

Advances in pathogenesis and clinical manifestations of myelofibrosis

骨髓纤维化是骨髓增殖性肿瘤的一种,预后差,生存期短。最近的研究对其发病的分子机制、临床表现及并发症都有进展,对此种疾病的临床诊断、治疗及预后评估都有帮助。本文对以上内容的研究进展进行综述。

Myelofibrosis is a kind of myeloproliterative neoplasms,prognosis is poor,overall survival is short. Recent studies on molecular mechanism of its pathogenesis,clinical manifestations and complications have new progress,this kind of disease in the clinical diagnosis,treatment and prognosis assessment is helpful. This paper reviewd research progress on the above content.