山茶汤与多索茶碱联合治疗矽肺病的效果研究

CLINICAL EFFECT OF COMBINED WITH HILL TEA AND DOXOFYLLINE IN THE TREATMENT OF SILICOSIS

目的观察山茶汤与多索茶碱联合使用在矽肺病治疗当中的作用。方法从该院2013年1月—2015年1月收治的矽肺病患者当中随机选取68例患者作为研究对象,并随机分为二组,其中对照组34例,观察组34例。对照组服用矽肺病治疗药物多索茶碱;观察组在对照组基础上服用山茶汤,每天1剂,连续服用6个疗程,每个疗程30d。在治疗过程中,对对照组以及观察组患者临床体征、肺总有效率、肺部X线变化以及红细胞C3b受体花环率(RBC-C3bRR)进行测定。结果采用山茶汤与多索茶碱联合治疗的观察组总有效率达到88.2%,远高于单独多索茶碱治疗的有效率(67.6%),两者之间差异有统计学意义;且治疗后,观察组患者肺总有效率、肺部X线以及以及红细胞C3b受体花环率相比于对照组而言均有较大程度改善,两者之间差异有统计学意义。结论山茶汤与多索茶碱联合治疗在矽肺病治疗过程中相比于多索茶碱而言效果更佳。

Objective To observe the effect of combined Hill tea and Doxofylline in the treatment of silicosis.Methods Totally 68 patients were randomly selected from author＇s hospital since 2013,which were randomly divided into two groups,34 cases in each group.In the experiment,the control group received drugs Doxofylline which was usually used for the treatment of silicosis;on the basis of control group,the observation group was given mountain tea,once a day,total for six courses,each course of 30 days.During treatment,the clinical signs,total efficiency of the lung,chest X-ray changes and erythrocyte C3b receptor rosette（RBC-C3bRR）were measured in two groups of patients.Results Compared with the total efficiency in control group（67.6%）,the total efficiency in observation group was 88.2%,and there was a significant difference between the two groups;and after treatment,the total efficiency of lung,chest Xray,as well as red blood cell C3b receptor rosette rate in the observation group were much better than that in the control group,there were significant differences between the two groups.Conclusion Compared with the exclusive use of Doxofylline,the combination therapy of Mountain tea and Doxofylline for silicosis is much better.