肝动脉栓塞化疗治疗肝癌的应用进展

Application progress of transarterial chemoembolization in the treatment of hepatocellular carcinoma

肝动脉栓塞化疗（TACE）结合了栓塞和化疗两种治疗方法.尽管TACE的临床疗效显著,但单独采用TACE仍无法治愈肝癌.栓塞难以完全、侧支循环建立和新生血管等原因大大影响其远期疗效.因此,TACE疗效的提高有赖于综合治疗.为此,本文从栓塞剂、化疗药物、联合治疗等方面就TACE在肝癌治疗中的应用现状及进展做一综述.

Transarterial chemoembolization （TACE） combined the embolization with chemotherapy,whose efficacy has been verified in the treatment of hepatocellular carcinoma.Factors like the incomplete embolism,the formation of collateral circulation,neoangiogenesis and the like greatly weaken the clinical efficacy of TACE in the long term.Thus,the improvement of TACE efficacy depends on the comprehensive treatment.This paper reviewed the present application status and the progress on the treatment of hepatocellular carcinoma with TACE.