某三甲医院专项整治前后抗菌药物应用情况对比分析

The Effect Evaluation of Special Rectification on the Rational Use of Antibioticsin in the Hospital

目的:评价抗菌药物专项整治活动对于规范西安医学院第一附属医院抗菌药物合理应用的效果。方法:收集抗菌药物专项整治活动开展前后5年的资料,分为整治前(2009年到2011年第二季度)和整治后(2011年第三季度到2013年),比较整治活动前后抗菌药物合理应用相关指标的变化。结果:整治活动后,抗菌药物季度销售金额从413万下降至328万,季度抗菌药物销售金额占全部药品销售的比率由26%降至15%;住院患者抗菌药物使用率从88%降至66%,抗菌药物使用强度从92.4DDDs/(100人·d)降至60.3DDDs/(100人·d);门诊患者抗菌药物处方从60%降至28%。结论:抗菌药物专项整治活动效果明显,加强抗菌药物的监管力度后,极大促进抗菌药物临床的合理用药。

Objective To evaluate the effect of special rectification on the rational use of antibiotics. Method The data of relate- dindex of antibiotics in the clinical application in fiveyears （from 2009 to 2013 ） were collected, which was divided into two groups based on the before and after the special rectification. The difference between intervention group and the control was fully analyzed. Results After the rectification, antibiotics sales was decreased from 4. 13 million to 3.28 million, with the sales ratio of drug revenues from 26% to 15%. Antibiotic utilization in hospitalized patients drops to 66%. The use intensity was decreased from 92.4 DDDs / （ 100 person, d） to 60. 3 DDDs/ （ 100 person, d）. Besides, the antibiotics prescriptions of patients in outpatient come down signif- icantly from 60% to 28%. Conclusion Special rectification of antibiotics has obvious effect on the rational use of antibiotics in our hos- pital, and it improves the management of clinical use of antibiotics in hospital.