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C1q/肿瘤坏死因子相关蛋白3和9在肥胖相关疾病中的作用 被引量：2

The Roles of C1q/TNF-related Protein-3(CTRP3) and C1q/TNF-related Protein-9(CTRP9) in Obesity Related Diseases
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摘要 C1q/肿瘤坏死因子相关蛋白3(CTRP3)和C1q/肿瘤坏死因子相关蛋白9(CTRP9)作为新的连接炎症和肥胖相关代谢疾病的抗炎脂肪因子之一,具有多种生物学功能。近年来针对CTRP3和CTRP9在肥胖相关疾病中的作用的研究成为热点,并发现其在肥胖相关的心血管疾病及糖脂代谢中发挥重要作用。就CTRP3和CTRP9的组织结构和功能及它们在肥胖相关疾病的发生发展中的作用进行综述。 As one of new anti-inflammatory adipokines factor with connection to inflammation and obesity related metabolic diseases, C1q/TNF-related protein-3（CTRP3） and C1q/TNF-related protein-9（CTRP9） have a variety of biological functions. Recently, studies of the roles in CTRP3 and CTRP9 targeted in obesity related diseases become hot, and found that they play an important role in obesity related cardiovascular disease and glucose-lipid metabolism. This article is objected to review organizational structure and function about CTRP3 and CTRP9,and its role in the development of obesity related diseases.
作者 王媛 刘戈力
机构地区 天津医科大学总医院儿科 天津市公安医院儿科
出处 《继续医学教育》 2016年第2期109-111,共3页 Continuing Medical Education
关键词 CTRP-3 CTRP-9 肥胖 心血管疾病 糖脂代谢 CTRP-3 CTRP-9 Obesity Cardiovascular disease Glucoselipid metabolism
分类号 R541 [医药卫生—心血管疾病]
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参考文献17

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  • 2Hofmann C, Chen N, Obermeier F, et al. Clq/TNF-related protein-3 ( CTRP-3 ) is secreted by visceral adipose tissue and exerts antiinflammatory and antifibrotie effects in primary human colonic fibroblasts[J]. Inflamm Bowel Dis, 2011, 17 (12): 2462-2471.
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继续医学教育
2016年 第2期

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