宫颈电圈环切术锥切治疗宫颈上皮内瘤变的临床应用研究

Clinical study of cervical loop electrosurgical excision conization in treatment of cervical intraepithelial neoplasia

目的探讨宫颈电圈环切术锥切在宫颈上皮内瘤变患者中的临床治疗效果。方法选取2014年10月～2015年10月医院诊治的100例宫颈上皮内瘤变患者资料进行分析,采用随机对照方法将患者分为对照组和实验组,对照组采用冷刀宫颈锥切术（CKC）,实验组采用宫颈电圈环切术锥切（TCRC）治疗,比较两组临床疗效。结果两组患者手术时间、术中出血时间差异无统计学意义（P〉0.05）;实验组术中出血量、创面完全结痂时间,显著少于对照组（P〈0.05）;两组患者二次手术率、CIN残留率差异无统计学意义（P〉0.05）;实验组治愈率,显著高于对照组（P〈0.05）;实验组复发率,显著低于对照组（P〈0.05）。结论宫颈上皮内瘤变患者采用宫颈电圈环切术锥切治疗效果理想,能够提高临床疗效,手术创伤较小,值得推广应用。

Objective To investigate the clinical effect of cervical loop electrosurgical excision conization in treatment of patients with cervical intraepithelial neoplasia. Methods From October 2014 to October 2015 in our hospital,100 cases of cervical intraepithelial neoplasia patients were analyzed by the method of randomized controlled,and they were divided into control group and the experimental group, the control group used cold knife conization（CKC）, the experimental group used cervical loop electrosurgical excision conization（TCRC） treatment, clinical efficacy was compared in two groups. Results The operative time, blood loss time of two groups had no significant（P〉0.05）; the blood loss, wound completely crusted time in experimental group was significantly less than the control group（P〈0.05）; the secondary operation rate, CIN residual rate of two groups had no significantly difference（P〉0.05）; the cure rate in experimental group was significantly higher than the control group（P〈0.05）; the recurrence rate of the experimental group was significantly lower than the control group（P〈0.05）. Conclusion The patients with cervical intraepithelial neoplasia cervical loop electrosurgical excision conization with ideal treatment effect, can improve the clinical efficacy, with less invasive surgery, should be widely applied.