盐酸丙卡特罗联合小儿伪麻美芬滴剂治疗喘息性支气管炎疗效观察

The therapeutic efficacy of procaterol hydrochloride combined with motrin in children with asthmatic bronchitis

目的探讨盐酸丙卡特罗联合小儿伪麻美芬滴剂治疗喘息性支气管炎的疗效。方法选择2013年12月～2014年12月我院儿科门诊确诊为喘息性支气管炎患儿130例,按就诊顺序分为治疗组和对照组各65例。对照组给予阿莫西林克拉维酸钾干混悬剂及雾化吸入;治疗组在对照组基础上采用盐酸丙卡特罗口服液1.25μg/kg（0.25 m L/kg）,每日2次;小儿伪麻美芬滴剂,0～3个月,0.4 m L/次,4～11个月,0.8 m L/次,12～23个月,1.2 m L/次,24～36个月,1.6 m L/次,每4～6小时口服,治疗7 d后评价两组疗效。结果治疗组有效率显著高于对照组（χ^2=34.43,P〈0.01）;对照组热退时间、咳止时间、喘止时间及肺部啰音消失时间分别为（3.14±0.56）d、（5.29±0.83）d、（5.44±0.69）d、（6.46±0.74）d,治疗组热退时间、咳止时间、喘止时间及肺部啰音消失时间分别为（2.62±0.63）d、（4.53±0.81）d、（4.83±0.78）d、（5.76±0.86）d,两组比较差异具有高度统计学意义（P〈0.01）。结论盐酸丙卡特罗联合小儿伪麻美芬滴剂治疗喘息性支气管炎疗效确切,值得推广应用。

Objective To explore the therapeutic efficacy of procaterol hydrochloride combined with motrin in children with asthmatic bronchitis. Methods A total of 130 children with asthmatic bronchitis in out-patient of department of paediatrics from December 2013 to December 2014,according to their consulting order,were divided into control group（n=65） and treatment group（n=65）. Patients in control group were taken dry suspension amoxicillin and clavulanate potassium and aerosol inhalation. Patients in treatment group were taken procaterol hydrochloride 1.25 μg/kg（0.25 m L/kg）with 2 times a day; motrin 0-3 month,0.4 m L per time,4-11 month,0.8 m L per time,12-23 month,1.2 m L per time,24-36 month, 1.6 m L per time,taken every 4-6 hours, and therapeutic effects in both groups were evaluated after 7 days.Results The effective in the treatment group was significantly higher than that in the control group（χ^2=34.43,P〈0.01）. The clinical data were compared between the two groups, the fever annealed time,cough stopped time,wheezing disappeared time, rale disappeared time in the control group were（3.14±0.56）days,（5.29±0.83）days,（5.44±0.69）days,（6.46±0.74）days, and the fever annealed time, cough stopped time, wheezing disappeared time, rale disappeared time in the treatment group were（2.62±0.63）days,（4.53±0.81）days,（4.83±0.78）days,（5.76±0.86）days, there were significant differences between two groups（P〈0.01）. Conclusion It has a definite therapeutic effect of procaterol hydrochloride combined with motrin in children with asthmatic bronchitis,and it deserves popularization and application.