降钙素原对小儿重症感染诊断价值

The value of calcitonin original in the diagnosis of severe infection in children and the analysis of the treatment of the guidance and treatment

目的探究降钙素原在小儿重症感染中有何诊断价值,并分析降钙素原在降阶梯治疗方案中的指导作用。方法选择2013年7月～2015年8月间在我院治疗疾病的患儿共300例,其中非感染者100例,局部细菌感染者100例,重症细菌感染者100例,将以上三组分别设为A组（非感染病症）、B组（局部感染）及C组（重症感染）。所有患儿入院后均予相应的针对性治疗。对比PCT等指标在治疗前后的变化,分析其对降阶梯治疗有何指导意义。结果 C组检查结果分别为PCT（4.84±1.02）ng/m L、WBC（11.96±3.85）、CRP（9.58±5.40）mg/L。其中CRP、PCT在治疗后有了显著改善,分别为（11.39±3.03）mg/L和（1.84±0.45）ng/m L。接受降阶梯治疗的指导组患者死亡率仅有2%,远低于传统组的14%。结论患儿感染病症的轻重可以通过PCT高低来实现准确的临床诊断,治疗中还可依据PCT的变化指导患儿改变临床用药,经指导的降阶梯治疗不仅可以降低医疗成本,还能减少过量使用抗生素带来的不良反应。

Objective To explore the calcitonin original what diagnostic value in children with severe infection,and analyze the calcitonin original guidance in the down stairs treatment. Methods A total of 300 cases with 100 cases of health,localized bacterial infection in 100 cases,from July 2013 to August 2015 in our hospital to treat disease of children,100 cases of severe bacterial infections will the above three groups respectively named the first division（infection） and group B（local infection）and group C（severe infection）. All children are corresponding targeted treatment after admission. Comparison of PCT,and other indicators in the change of the before and after treatment,to analyze its treatment in the down stairs what implications. Results The PCT,the WBC and CRP level of group C was higher than that in the other two groups（P〈0.05）,the statistical difference; Points within the steering group of treatment was better than the traditional group,the statistical difference was significant（P〈0.05）. Conclusion The weight of the infection in children with symptoms can be done by applying high and low accurate clinical diagnosis and treatment can also according to change of PCT in clinical medication guide children to change, by the guidance of ladder treatment can not only reduce the medical cost,also can reduce the bad reaction caused by excessive use of antibiotics.