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卵母细胞形态异常对辅助生育预后情况的影响 被引量:1

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摘要 目的探讨卵母细胞形态异常对辅助生育预后情况的影响。方法收集2012年1月至2013年12月于本中心行黄体期长方案IVF助孕治疗(排除ICSI及补救ICSI治疗周期)的患者,共1 452个治疗周期,根据卵母细胞形态不同分为9种形态异常类型,另外选择500个形态正常的卵母细胞为对照组,比较形态异常组与对照组的2PN受精率、优质卵裂胚率、优质囊胚率、卵母细胞利用率。结果与对照组比较,9种卵母细胞形态异常组中,极体异常对2PN受精率、优质囊胚率、卵母细胞利用率的影响最为显著,上述指标均显著降低(P<0.05);卵母细胞体积大的组别优质卵裂胚率显著低于对照组(P<0.05)。结论极体异常与卵母细胞体积变大对辅助生育预后情况有显著影响,可用于植入前的胚胎质量评估。
出处 《生殖医学杂志》 CAS 2016年第2期174-178,共5页 Journal of Reproductive Medicine
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