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动脉血乳酸清除率与ICU危重患者预后的关系 被引量:5

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摘要 目的 探讨动脉血乳酸清除率与ICU危重患者预后的关系。方法 选择衡水市第二人民医院重症医学科入住的142例危重症患者行动脉血乳酸水平测定,分别在入住ICU 30 min内、6、12、24、48、72 h后分别进行血乳酸测定,观察血乳酸水平与预后及病死率的相关性。计算治疗后6、24 h动脉血乳酸清除率,采用急性生理及慢性健康状况评估Ⅱ(APACHE-Ⅱ)评分系统分别于治疗前和治疗后72 h对患者进行评分。结果 治疗后6 h内动脉血乳酸清除率≥10%的患者62例、6-24 h内动脉血乳酸清除率≥10%的患者64例、24 h动脉血乳酸清除率〈10%的患者16例,病死率分别为12.9%(8/62)、31.8%(20/64)、81.3%(13/16),治疗后6、24 h病死率与28 d差异有统计学意义(P〈0.05)。治疗后6、24 h APACHE-Ⅱ评分、心率、呼吸、Pa O2/Fi O2、p H值、动脉血乳酸与28 d比较,差异有统计学意义(P〈0.05)。全部患者治疗后存活101例、28 d死亡41例,治疗后24 h动脉血乳酸清除率≥10%126例、24 h动脉血乳酸清除率〈10%16例,病死率分别为22.2%(28/126)、81.3%(13/16)。结论 动脉血乳酸清除率与ICU危重患者预后密切相关,及早恢复动脉血乳酸的正常值可改善危重患者的预后。
出处 《河北医药》 CAS 2016年第2期240-242,共3页 Hebei Medical Journal
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