胃癌荧光分子成像研究进展

Advance of fluorescence molecular imaging in gastric cancer

荧光分子成像技术是近年来发展迅速的一种新兴分子成像技术，应用广泛。随着特异性靶向胃癌荧光分子探针的不断研发，荧光分子成像技术在胃癌临床前研究中的信噪比得到了显著提高；由该技术与内镜技术结合而成的新型的荧光内镜，也是胃癌临床前研究中的有效工具。相信随着研究的不断深入，荧光分子成像技术将在胃癌的临床诊断中发挥重要作用。笔者就其在胃癌诊治领域应用进展进行综述。

Fluorescence molecular imaging technology （FMIT） has been developing rapidly in recent years. Following the development of fluorescent probes specifically targeted for gastric cancer, the signal to noise ratio has been improved in preelinieal study. By combing with endoscopic technology, a new imaging modality called fluorescence endoscopy has been established and it is useful for the detection of gastric cancer in preelinieal study. FMIT might be a promising modality in the clinical diagnosis of gastric cancer. This review summarizes the application of FMIT in preelinieal studies of gastric cancer.