补肝汤对亚健康疲劳状态大鼠肝脏及腓肠肌组织形态学的影响

Effects of Bugan Decoction on the morphology of the liver and gastrocnemius muscle of fatigue rats induced by sub-health

目的:观察补肝汤对亚健康疲劳状态大鼠肝脏及腓肠肌组织形态学的影响,深入探讨补肝汤治疗亚健康疲劳状态的机制。方法:将大鼠分为正常组、模型组、治疗组;分别进行造模、给药;实验结束取大鼠肝脏,腓肌组织进行HE染色,观察各组大鼠肝脏、腓肠肌组织形态学的改变,分析补肝汤的治疗效果。结果:治疗组大鼠肝脏、腓肠肌组织结构的形态学改变与正常组比较无明显差异;治疗组大鼠肝脏、腓肠肌组织结构的形态学改变较模型组有明显改善。结论:补肝汤可以改善亚健康疲劳状态大鼠的肝脏、腓肠肌组织结构的形态学改变,可以有效地缓解大鼠的疲劳症状。

Objective：To observe the effects of Bugan Decoction on the morphology of the liver and gastrocnemius muscle of fatigue rats induced by sub-health,and go deeply into the mechanism of Bugan Decoction in the treatment of the fatigue induced by sub-health.Methods：All of rats were randomly divided into the control group,model group and treatment group.Changes in the morphology of the liver and gastrocnemius muscle were observed with a light microscope.Results：There was no significant difference in the morphology of the liver and gastrocnemius muscle between the control group and the treatment group.The morphology of the liver and gastrocnemius muscle in the treatment group,however,was significantly improved,compared with that in the model group.Conclusion：Bugan Decoction could improve the morphology of the liver and gastrocnemius muscle of fatigue rats induced by sub-health,for the reason that the rat’s fatigue symptoms were effectively relieved.