眼内注C_3F_8治疗有玻璃体眼的II期黄斑裂孔

Intravitreal C_3F_8 injection for treatment of stage II idiopathic macular hole

目的探讨单纯眼内注入惰性气体C3F8治疗II期黄斑裂孔临床疗效察。方法选取19例单纯II期黄斑裂孔患者,术前行视力及黄斑OCT检查,于距睫状体平坦部4 mm行玻璃体腔内注入C3F8气体0.30.6ml,术中指测眼压Tn,光感明确后,行严格俯卧位休息,术后行黄斑OCT检查,及矫正视力检测。结果术后观察3个月至1年,术后黄斑裂孔闭合的有17只眼,总有效率为89.47%,术前及术后视力行t检验,P〈0.05,有统计学意义。结论有玻璃体眼的单纯II期黄斑裂孔行眼内注C3F8可有效的封闭裂孔。

Objective To investigate the clinical effects of intravitreal C3F8 injection for the treatment of stage II idiopathic macular hole（ IMH）.Methods Clinical data of 19 IMH patients（19 eyes） were retrospectively analyzed.All patients were stage II macular hole.Visual acuity and OCT examinations were performed before surgery.C3F8 was injected4 mm posterior to ciliary body pars plana into vitreous（0.30.6 ml）.IOP and visual function（ light perception） were monitored during the procedure.Patients were then advised to maintain strict prone position.Macular optical coherence tomography（ OCT） and corrected visual acuity were examined later.Results Patients were followed up for 3 months to 1 year.Macular hole closure was achieved in 17 eyes,with total effective rate 89.47%.Visual acuity improved significantly（P〈0.05）.Conclusion Uncomplicated stage II idiopathic macular hole can be effectively treated with vitreous C3F8 injection.