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微流控法DNA片段化研究进展 被引量：1

Recent Progress of DNA Fragmentation Based on Microfluidics
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摘要 DNA分子的片段化技术对于下一代基因测序技术和疾病检测技术意义重大,文章回顾了现有的DNA片段化方法,着重介绍了基于微流控芯片技术的流体动力学剪切法DNA片段化技术,总结了影响微流控芯片中DNA片段化过程的因素,并且展望未来微流控技术在DNA片段化和生物芯片领域的应用. DNA fragmentation is one of the key technologies for gene library and disease detection. Normal DNA fragmentation technologies are reviewed focusing on microfluidic based DNA fragmentation technology. Effective pa- rameters are discussed and summarized according to the resulted DNA fragments. The importance and perspective of microfluidic DNA fragmentation are summarized.
作者 水玲玲 李岚慧 金名亮 周国富
机构地区 华南师范大学华南先进光电子研究院
出处 《华南师范大学学报（自然科学版）》 CAS 北大核心 2016年第1期23-27,2,共5页 Journal of South China Normal University(Natural Science Edition)
基金 国家自然科学基金项目(51405165) 教育部“长江学者和创新团队发展计划”项目(IRT13064) 广东省引进创新科研团队计划项目(2011D039)
关键词 微流控 DNA片段化 流体剪切 基因测序 microfluidics DNA fragmentation fluidic shearing gene sequencing
分类号 TN27 [电子电信—物理电子学]
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参考文献22

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华南师范大学学报（自然科学版）
2016年 第1期

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