中药联合氩氦刀“绿色治疗”模式对44例老年晚期非小细胞肺癌患者的生存影响

Survival effect of 44 cases of elderly patients with advanced NSCLC: A “Green Therapeutic” mode combined with both percutaneous cryoablation and TCM herbal formula

目的对老年晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者进行中药汤剂口服联合氩氦刀冷冻治疗的生存影响进行临床观察分析。方法采用前瞻性研究方法,共观察90例老年晚期NSCLC患者氩氦刀冷冻前后生活质量的变化、局部瘤灶的复发转移情况及生存期并进行统计分析。结果治疗组、对照组的中位生存期分别为14个月、11个月。根据Karnofsky功能状态评分标准及生活质量评分标准(QOL),在患者术前和术后3个月、6个月生活质量变化,局部瘤灶转移率,氩氦刀术后中位生存期及1年、18个月的生存率方面,P<0.05,治疗组优于对照组。结论中药联合氩氦刀的"绿色治疗"模式对44例老年晚期NSCLC患者的生存影响方面具有明显意义。

Objective To obserle the surlilal effect of TCM herbal formula with percutaneous cryoablation therapy in elderly adlanced non-small cell lung cancer. Methods 90 patients with elderly adlanced non-small cell lung cancer （ NSCLC ） were dilided into treatment group （ n=44 ） and control group （ n=46 ） according to the patients ＆#39; wishes to obserle, statistical recordings of changes of life quality, the probability of tumor recurrence, metastasis as well as lifetime. Results The surlilal median in the treatment group and control group is 14 months, 11 months respectilely. According to Karnofsky functional status grading standard and quality of life marking standard （ QOL） , the treatment group was superior to control group in the quality of life changes of preoperatile and postoperatile 3 months, 6 months, the metastasis rate local tumor , the median surial time after percutaneous cryoablation and the surlilal of 1 year, 18 months （P〈0. 05）. Conclusions The ＆quot;Green Therapeutic＆quot; mode combined with TCM herbal formula and percutaneous cryoablation has significant meaning in the surlilal effect for 44 cases of elderly patients with adlanced NSCLC.