中文发表的非小细胞肺癌随机对照试验摘要报告质量评价

Assessment of abstracts on randomized controlled trials in non-small cell lung cancer published in Chinese

目的:评价中文发表的非小细胞肺癌(NSCLC)随机对照试验(RCT)摘要报告质量及其影响因素。方法:纳入中文发表的NSCLC领域的RCT,依据"摘要CONSORT"声明的标准评价纳入RCT的报告质量,采用Rev Man 5.3软件统计分析报告质量的影响因素。结果:纳入的2677篇RCT的摘要撰写尚存在欠缺,严重报告不足(小于20%)的条目为"题目判定为随机"、"随机化"、"盲法"、"统计方法"、"招募对象"、"实验注册"和"资助"。结论:中文发表的NSCLC的RCT摘要报告实施盲法的文献严重欠缺,特别是题目判定为随机、随机化、盲法、统计方法、招募对象、实验注册和资助报告严重不足,"摘要CONSORT"发表后报告质量有所改善,但还需提高。

Objective To assess the abstracts on randomized controlled trials （RCT） in non-small cell lung cancer （NSCLC） published in Chinese and their influencing factors. Methods RCT in NSCLC published in Chinese were included according to the CONSORT statement and their influencing factors were analyzed by RevMan 5.3 soft- ware. Results The titles were identified as random, randomization, blinding, statistical method, recruited partici- pants, trial registry and fund-supported, respectively, in 20% of the 2677 abstracts included in this study. Con- clusion The titles are identified as random, randomization, blinding, statistical method, recruited participants, trim registry and fund-supported in RCT published in Chinese. Although the abstracts are improved after the publication of CONSORT, they need to be further brushed uP.