磁分散萃取-液相色谱法测定食品接触材料中3种酚类物质迁移量

Determination of migration of three kinds of phenolic compounds from food contact materials using magnetic dispersion extraction-high performance liquid chromatography

目的合成一种表面多孔结构的磁性微球,用于食品包装材料迁移物的吸附富集,实现高灵敏度检测痕量组分。方法采用一锅法合成羧基化磁性微球,再经自组装法制备磁性金属有机骨架复合材料,并以此作为萃取剂,建立磁分散萃取-高效液相色谱法分离分析聚碳酸酯（PC）水杯中酚类化合物迁移量的新方法。结果平均回收率为85.36%~95.47%,相对标准偏差（RSD,n=5）为1.28%~5.64%,检出限和定量限分别为1.24~2.14 ng/m L和4.15~7.12 ng/m L。结论该合成方法简便可行,其磁性复合微球吸附性能好。该萃取和检测方法具有操作简便快速、富集倍数较高、灵敏度和准确度较好的特点,适用于酚类化合物的分离分析。

Objective To synthesize a kind of magnetic microspheres with porous surface for adsorption enrichment and highly sensitive analysis of the migration of phenols from food packaging material. Methods Carboxylated magnetic microspheres were synthesized by one pot method, and then magnetic metal-organic frameworks （MOFs） were prepared by layer self-assembly technique. The MOFs were used as adsorbent for magnetic dispersion extraction of migratory quantity of phenolic compounds from polycarbonate bottles. Results The average recoveries were in the range of 85.36%~95.47% with the RSD of 1.28%-5.64%. The limits of detection and quantitation of the proposed method were in a range of 1.24~2.14 ng/mL and 4.15~7.12 ng/mL, respectively. Conelusion The synthetic method of the magnetic MOFs is simple and feasible, and its adsorption performance is satisfactory. The extraction and detection method is simple, rapid and high enrichment factors with satisfactory precision and accuracy, and is suitable for the separation and analysis of the phenolic compounds.