扩张型心肌病心衰患者采用曲美他嗪治疗对改善LVEF、LVEDD、CO水平的作用

Dilated Cardiomyopathy Patients with Heart Failure Trimetazidine Treatment the Effect to Improve LVEF, LVEDD, CO Levels

目的针对扩张型心肌病心力衰竭患者采用曲美他嗪治疗对改善LVEF、LVEDD、CO水平的作用进行研究.方法：随机选择2012年12月～2015年9月期间,我院收治的扩张型心肌病心力衰竭患者120例,作为本次研究的对象,将其平均分为对照组和观察组.观察组患者实施曲美他嗪治疗,对照组实施常规抗心力衰竭治疗,针对两组患者的治疗效果、不良反应和LVEF、LVEDD、CO水平等指标进行观察比较.结果：在本次研究中,观察组和对照组患者的临床治疗有效率分别为96.67%、80.00%,经比较,P〈0.05,具有统计学意义.观察组和对照组患者的不良反应发生率分别为5.00%、11.67%,经比较,P〉0.05,无统计学意义.观察组患者治疗后的LVEF、LVEDD、CO水平与治疗前的比较,P〈0.05,具有统计学意义.对照组患者治疗后的LVEF、LVEDD、CO水平与治疗前的比较,P〈0.05,具有统计学意义.观察组患者治疗后的LVEF、LVEDD、CO水平与对照组患者治疗后的个指标水平进行比较,P〈0.05,具有统计学意义.结论：在扩张型心肌病心力衰竭患者治疗的过程中,对其实施曲美他嗪治疗,可以显著提高患者的临床治疗效果,改善患者的超声心动图相关指标,安全性较高.

Objective: To research DCM patients with heart failure with trimetazidine treatment to improve the level of LVEF and LVEDD,CO the effect.Methods:Randomly selected during December 2012 to September 2015,our hospital 120 cases of patients with dilated cardiomyopathy and heart failure,as the research object,its averaged were divided into control group and observation group.observation group patients implemented trimetazidine treatment,control group routine heart failure treatment,for the therapeutic effect of two groups of patients,adverse reactions,and LVEF and LVEDD,CO level indicators were observed and compared.Results:In this study,observation group and control group in patients with clinical treatment efficiency were 96.67%,80.00%,by compared,P<0.05,there was statistical significance.observation group and control group patients the incidence of adverse reactions Respectively were 5.00%,11.67%,was compared,P>0.05,there was no statistical significance.Observation group after treatment in patients with LVEF and LVEDD,CO level compared with before treatment,P<0.05,there were statistical significance.The control group after treatment in patients with LVEF and LVEDD,CO level compared with before treatment,P<0.05,there were statistical significance. Observation group after treatment in patients with LVEF and LVEDD,CO level and the control group after treatment in patients with a horizontal compared,P<0.05,there were statistical significance.Conclusion:In patients with dilated cardiomyopathy and heart failure in the process of treatment,the implementation of trimetazidine treatment,can significantly improve the clinical treatment effect of patients,improve echocardiography in patients with related indicators,safety is higher,so can be trimetazidine treatment in clinical application.