人类杏仁核与情感调节的研究进展

Progress on research of human amygdala and emotion control

目的 探讨杏仁核与人类情感调节之间的关系。方法在Pubmed及CNKI数据库系统分别以“amygdala，emotioncontrol”和“杏仁核、情感调节”为关键词查阅1999年9月-2014年9月有关杏仁核与情感调节的相关文献，进行分析总结。结果动物实验研究显示，杏仁核是恐惧形成和表达的关键中枢，是情感调节的基础，杏仁核可能通过递质释放达到调节情感的作用。人类的杏仁核是大脑边缘系统的一部分，附着在海马的末端，与人脑各部分间形成广泛的联系。在伴随情感变化的疾病中，杏仁核的组织结构和功能发生变化，参与人类情感的调节。临床上可以通过调节杏仁核的功能影响情感的调节，指导相关疾病的治疗。结论人类杏仁核是大脑边缘系统的重要组成部分，在人类的情感调节过程中发挥着重要作用。对杏仁核的功能的深入了解，可为临床疾病的诊断和治疗提供可靠理论基础。

Objective To explore the relationship between the amygdala and human emotion control. Methods With“ amygdala, emotion control” and “：杏仁核,情感调节” as key words to searchliteratures in PubMed and CNKI database from September 1999 to September 2014 and analyze. Results Experimental study on animals shows that the amygdala is a key hub formation and expression of fear, and isthe basis of emotion regulation, and possibly through the amygdala to regulate neurotransmitter release emotional effect. The amygdala is a part of the limbic system in human brains, attached to the end of thehippocampus, and between the human brain and various parts forming extensive contacts. In the emotional changes accompanving diseases, the amygdala structure and function changes involved in the regulation ofhuman emotions. The clinical related diseases can be treated by adjusting the amygdala function. Conclusions In-depth understanding of the function of amygdala can provide a reliable theoretical basis forclinical diagnosis and treatment of disease.