1986～2015年8月SCI数据库临床分子诊断的文献分析

Bibliometric Analysis of Ciinical Molecular Diagnosis Based on SCI Database from 1986 to Aug. 2015

目的采用文献计量的方法分析临床分子诊断的文献分布情况和研究概况。方法以Web of Sciences核心合集为数据库，以“molecular diagnosis”为主题词检索相关文献，时间跨度为1986年～2015年8月31日。使用Web of Sciences网站自带的分析工具对检索得到的结果和引文报告进行计量分析，分析内容包括：年出版文献量、每年的引文数、国家／地区的发文量排名、科研机构的发文量排名、收录相关论文最多的出版物排名，被引频次与施引文献汇总和总被引频次排名前十位的文章。结果共检索得到相关文献6279篇，年发表论文与引文数逐年递增，美国与西欧发达国家发文量较大，所有文献平均单篇被引16．6次，h—index为118，临床分子诊断技术在疾病的诊断、治疗和预后预测方面的文章具有较多的引用频次。结论临床分子诊断技术正处于学科发展的黄金阶段，其在疾病的诊疗中具有较大作用，在临床中的应用可提高我们的医疗水平。

Objective To analyze literature distribution and research of clinical molecular diagnosis in recent years using bibliometric method. Methods The ＂clinicalmolecular diagnosis＂ as the toplc,the papers related to clinical molecular diagnosis were searched from the database of ＂Web of Sciences＂ （from 1986 to 2015.8.31）. The resulting papers were analyzed using bibliometric method concerning the paper numbers, countrles/districts, institutes, journal distribution, etc. Summary of the times cited and citing papers were also investigated. Results k total of 6 279 papers were obtained from the database,and the annual number of publications and citations increased all the time. United States and West European countries （France, Italy,Germany,England,Spain, etc. ） issued the largest number of papers. The mean number of citation and h-index were 16.6 times and 118,respectively. The papers about the usage of clinical molecular diagnosis on disease diagnosis, treatment and prognosis had the most citations. Conclusion Clinical molecular diagnostics technology is in the development stage. It plays a larger role in the diagnosis and treatment of disease. The application of this technology may improve our services level significantly.