阿司匹林持续服用对急诊下行阑尾切除术中和术后出血的影响

Impact of continuous use of aspirin on intraoperative and postoperative bleeding in emergency appendectomy

目的分析阿司匹林持续服用对急诊下行阑尾切除术中和术后出血及其他并发症的影响。方法急性阑尾炎患者66例,其中持续应用阿司匹林组25例,未服用阿司匹林组41例。均急诊行阑尾切除术。比较两组术中出血量、手术时间、放置腹腔引流管率(引流量)、术后出血(再手术)率、术后输血率、切口感染率、血栓栓塞事件率住院时间及病理类型。结果两组患者在术中出血量、手术时间、放置腹腔引流管率、术后出血(再手术)率、术后输血率、切口感染率、血栓栓塞事件率、住院时间、病理类型等方面比较,差异无统计学意义(P>0.05)。结论在细致的操作及妥善的止血下,急诊下行阑尾切除患者围手术期持续服用低剂量阿司匹林是安全的,并不增加术中和术后出血风险。所以不建议拖延手术。

Objective To study the impact of continuous use of aspirin on intraoperative and postoperative bleeding and associated complications in emergency appendectomy. Methods There were 66 cases of acute appendicitis ,including 25 cases with continuous use of aspirin and 41 cases without it. The intraoperative bleeding, operating time, abdominal drainage rate, postoperative bleeding rate （ reopera- tion rate）, postoperative blood transfusion, incision infection rate, hirombaerinbolism cases, hospital stays and pathological patterns were compared. Results The two groups showed no significant difference in in- traoperative bleeding, operating time, abdominal drainage rate, postoperative bleeding rate （ reoperation rate） , postoperative blood transfusion, incision infection rate, hirombaerinbolism cases rate, hospital stays and pathological patterns（P 〉 0.05 ）. Condusion Continuous use of low-dose aspirin did not increase the rate of intraoperative and postoperative bleeding in the perioperative period in patients with who underwent emergency appendectomy. We do not recommend to postpone surgery.