植入式静脉输液港预防恶性肿瘤化疗患者并发症的效果

Prevention of complications in tumor chemotherapy patients by implantable venous infusion port

目的探讨植入式静脉输液港预防恶性肿瘤化疗患者并发症的效果。方法选取2011年10月至2014年10月间收治的106例肿瘤化疗患者,根据随机数字表法分为观察组和对照组,每组各53例。观察组患者行植入式静脉输液港治疗,对照组患者行外周静脉置入中心静脉导管治疗,比较两组患者的并发症发生情况。结果观察组患者导管堵塞发生率为(0.0%)、导管相关性感染发生率为(3.8%)、药液外渗发生率为(1.9%)、导管脱落或断裂发生率为(0.0%)、血栓发生率为(0.0%)、Pinch-off综合征发生率为(0.0%)均明显低于对照组(分别为7.5%、17.0%、13.2%、7.5%、9.4%和7.5%),差异均有统计学意义(均P<0.05)。结论植入式静脉输液港可显著降低肿瘤化疗患者并发症发生率,值得临床推广使用。

Objective To investigate prevention of complications in tumor chemotherapy patients by implantable venous infusion port. Methods From October 2011 to October 2014, 106 tumor chemother- apy patients who received treatment in Beijing Shijitan Hospital were selected and randomly divided into ob- servation group and control group, with 53 cases in each group. Patients in observation group were treated by implantable venous infusion port. Patients in control group were treated by peripherally inserted central catheters. Complications between two groups were compared. Results Incidence of catheter blockage （0.0%）, catheter related infection （ 3.8% ）, extravasation （ 1.9% ）, catheter shedding or fracture （0.0%） , thrombosis （0. 0% ） , Pinch-off syndrome （0. 0% ） in observation group were significantly lower than those of control group （7. 5%, 17.0% , 13.2%, 7.5% , 9.4% , 7.5% , respectively）, all with sig- nificant differences （ P 〈 0. 05 ）. Conclusion Implantahle venous infusion port can significantly reduce in- cidence of complications in tumor chemotherapy patients. It is worth clinical promotion.