有氧运动训练对老年原发性高血压病脉压指数的影响

Effect of Aerobic Exercise Training on Pulse Pressure Index in Elderly with Primary Hypertension

目的:探讨有氧运动训练对老年原发性高血压病患者脉压指数的影响。方法:老年原发性高血压病患者60例,随机分为2组各30例,A组予常规降压治疗,B组在此基础上予每周4次低中强度有氧训练,随访6个月,观察2组治疗前后血压、血脂、脉压(PP)和脉压指数(PPI)及血浆致动脉硬化指数(AIP)水平的变化。结果:随访6个月时,2组收缩压、舒张压均较治疗前明显下降(P<0.05),且B组的收缩压显著低于A组(P<0.05),而2组间的舒张压比较差异无统计学意义;随访6个月时,2组患者的血脂及AIP分别与治疗前比较均差异无统计学意义,但B组的血脂及AIP均显著低于A组(P<0.05);治疗2、4及6个月时,B组的PP均低于A组(P<0.05);治疗2、4及6个月时,A组较治疗前比较差异无统计学意义,而B组在随访4及6个月时的PPI较治疗前显著降低(P<0.05),且在治疗6个月时,B组的PPI显著低于A组(P<0.05)。结论:长期规律的有氧运动训练可以改善老年高血压病的脉压指数,延缓动脉硬化进程。

Objective：To investigate the effect of aerobic exercise training on pulse pressure index（PPI）in elderly patients with primary hypertension.Methods：Sixty aged patients with hypertension were randomly divided into two groups：group A for the control group,and group B for aerobic exercise training group.Group A was given the conventional antihypertensive treatment.Group B received the low or medium intensity aerobic exercise（4times every week）on the basis of conventional antihypertensive therapy.The changes in blood pressure,lipids,PP,PPI and atherogenic index of plasma（AIP）levels of the two groups were observed during the treatment within the follow-up period of six months.Results：The systolic and diastolic blood pressure in two groups was significantly decreased after treatment for 6months（P〈0.05）.The systolic blood pressure in group B was significantly lower than in group A（P〈0.05）,and the diastolic blood pressure between the two groups had no obvious difference（P〉0.05）after treatment for 6months.Before and after treatment for 6months,the lipids and AIP in two groups had no significant difference（P〉0.05）.Between the two groups,the lipids and AIP in group B were significantly lower than those in group A（P〈0.05）.The PP was followed up at 2nd,4th and 6th month respectively,and PP in group B was lower than that in group A（P〈0.05）in the above periods.The PPI in group A was followed up at 2nd,4th and 6th month,and there was no statistically significant difference before and after treatment（P〉0.05）.The PPI in group B was reduced remarkably at 4th and 6th month as compared with pretreatment（P〈0.05）.At 6th month after treatment,PPI in group B was significantly lower than in group A（P〈0.05）.Conclusion：Long-term regular aerobic exercise training can decrease the PPI of elderly hypertensive patients,delaying the development of atherosclerosis.