肠道菌群与大肠癌关系研究进展

Relationship between gut microbiota and colorectal cancer

大肠癌是人类常见的恶性肿瘤之一,在我国发病率逐年上升,其发病机制复杂,与遗传、环境等诸多因素有关。近年来,研究表明肠道菌群及其代谢产物与大肠癌密切相关。同时,肠道菌群也是导致炎症产生的主要因素,并且与大肠癌的发生密切相关。本文就肠道菌群及其代谢产物和炎症在大肠癌中的作用作一概述。

Colorectal cancer is one of the common malignant tumors, its incidence increases year by year in our country, its pathogenesis is complex and associated with genetic, environmental and many other factors. In recent years, researches show that the gut microbiota and its metabolites are closely related to colorectal cancer. At the same time, gut microbiota is the main factor leading to inflammation, and it is closely related with the occurrence of colorectal cancer. In this paper, the role of gut microbiota, their metabolites and inflammation in colorectal cancer was reviewed.