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我院临床常用药物代谢规律、相互作用及不良反应简表的建立

Establishment of statistical tables for the metabolic rules, interactions and adverse reactions of drugs generally used in clinic
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摘要 目的 :对我院临床常用药物的代谢规律、相互作用和不良反应相关资料进行统计,为预测个体患者药物治疗效果和不良反应的发生提供参考。方法 :对临床各科室的用药情况进行调查,统计和归纳。结果 :各科室用药特点不一,统计简表的建立可在很大程度上减少潜在的用药风险和不良反应。结论 :药物使用的统计资料能为临床治疗方案的制定提供参考,可提高患者的依从性,避免可能发生的不良反应和事件。 Objective: To add up the metabolic rules, interactions and adverse reactions of drugs generally used in clinic in our hospital to provide a reference for prediction of the efficacy and adverse reactions in individual patient. Methods: The data of clinical medication from departments of our hospital were investigated and statistically inducted. Results: Because there were differences of medication among departments, the establishment of statistical tables could reduce the potential risks of medication and adverse drug reactions to great extent. Conclusion: The statistics of drug use can provide a reference for the formulation of clinical treatment programs, improve patient compliance, and avoid the possible occurrence of adverse reactions and events.
机构地区 上海市同济医院
出处 《上海医药》 CAS 2016年第3期54-57,共4页 Shanghai Medical & Pharmaceutical Journal
关键词 药物代谢 不良反应 相互作用 drug metabolism drug interactions adverse drug reactions
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  • 1李江利,卫江英,王凯伟.西沙必利的临床应用和注意事项[J].武警医学,2006,17(3):221-223. 被引量:7
  • 2SCHROEDER W ,Ghobrial L ,Gandhi P. Possible mechanisms of drug-induced aspirin and clopidogrel resistance [J].Journal of Thrombosis and Thrombolysis, 2006,22 ( 2 ) : 139- 150.
  • 3COZZA K L, ARMSTRONG S C, OESTER HELD J R. Drug interactions by medical specialty. In:Concise Guide to Drug Interaction Principles for Medical Practice: Cytochrome P450s, UGTs, P-Glycoproteins [M]. 2nd ed. Washington D C: American Psychiatric Pub, 2003,167-396.
  • 4ZEVIN S, BENOWITZ N L. Drug Interactions with Tobacco Smoking : An Update[J]. Clinical Pharmacokinetics, 1999,36 : 425-438.
  • 5DE LEON J, DIAZ F J, ROGERS T, et al. A pilot study of plasma caffeine concentrations in a US sample of smoker and nonsmoker volunteers [J]. Prog Neuropsychopharmaeol Biol Psychiatry, 2003,27 (1) : 165-171.
  • 6NGUYEN M ,CHUNG E P. Telithromycin :The first ketolide antimicrobial [J]. Clinical Therapeutics, 2005,27 (8) : 1144-1163.
  • 7SLAUGHTER R L, EDWARDS D J. Recent advances: the cytochrome P450 enzymes [J].Ann Pharmacother, 1995,29 : 619-624.
  • 8WEINSHILBOUM R. Inheritance and Drug Response [J]. N Engl J Med,2003,348(6): 529-537.
  • 9[Anonymous] Special report: genotyping for cytochrome P450 polymorphisms to determine drug-metabolizer status[J]. Technol Eval Cent Asses Program Exec Summ, 2004,19 : 1-2.
  • 10MICHALETS E L. Update :clinically significant cytochrome P-450 drug interactions [J]. Pharmacotherapy, 1998,18 : 84-112.

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