奥洛他定及双氯芬酸钠滴眼液联合治疗过敏性结膜炎88例

Olopatadine Combined with Diclofenac Sodium Eye Drops for Treating Allergic Conjunctivitis in 88 Cases

目的观察奥洛他定滴眼液联合双氯芬酸钠滴眼液治疗各种类型过敏性结膜炎的临床疗效。方法将过敏性结膜炎患者176例随机分为对照组和观察组,各88例。观察组使用奥洛他定联合双氯芬酸钠滴眼液治疗,对照组单用奥洛他定滴眼液治疗,分别于治疗前与治疗后7,14 d比较患者症状与体征的变化,评价疗效。结果治疗7 d后,观察组和对照组有效率分别为69.32%与48.86%,治疗14 d后分别为88.64%及71.59%,观察组均显著高于对照组(P<0.05)。结论奥洛他定联合双氯芬酸钠滴眼液对过敏性结膜炎疗效较好。

Objective To evaluate the clinical efficacy of olopatadine combined with diclofenac sodium eye drops for the treatment of al- lergic conjunctivitis. Methods 176 patients with allergic conjunctivitis were chosen and divided into two groups： the observation group （n =88） treated with olopatadine and diclofenac sodium; the control group（ n =88） just received olopatadine. The symptoms and signs were observed at the 7 d and 14 d before and after the treatment, respectively. The clinical efficiency were evaluated. Results Efficacy rate of the 7 d after administration of the observation and control group were 69.32% and 48.86%, and 14 days after administration were 88.64% and 71.59%, respectively（P 〈 0. 05）. Conclusion Olopatadine combined with diclofenac sodium treatment significantly improves the efficacy of patients with allergic conjunctivitis.