阴道超声检查及血清β-HCG、孕酮检测在早期输卵管妊娠诊断中的应用及评价

Application and evaluation value of combined detection of transvaginal ultrasonography and serumβ-HCG、progesterone in the diagnosis of early tubal pregnancy

目的探讨阴道超声检查及血清β-HCG、孕酮检测在早期输卵管妊娠诊断中的应用价值。方法选择早期输卵管妊娠患者50例为研究组,正常宫内妊娠50例为对照组。对所有患者进行经阴道超声检查和定量血清β-HCG、孕酮检测,同时分析3种检测方式的诊断符合率。结果研究组两次血β-HCG、血孕酮值均明显低于对照组,差异有显著性(均P<0.05),且48h后复查β-HCG发现,对照组β-HCG上升幅度明显高于研究组,达到1.96倍;阴道超声检查结果显示,研究组子宫内膜厚度、附件区包块大小显著大于对照组(均P<0.05),盆腔积液含量略高于对照组,但差异无统计学意义(P>0.05)。两组3项联合检测的诊断符合率均显著高于单独血清β-HCG、孕酮和子宫内膜厚度检测的符合率(P<0.05)。结论阴道超声检查和血清β-HCG、孕酮检测联合应用,可有效地提高早期输卵管妊娠的诊断率,应在临床上加以推广、普及。

Objective To study the application value of combined detection of transvaginal ultrasonography and Serum 13-HCG,progesterone in the diagnosis of early tubal pregnancy. Methods Selecting 50 patients with early tubal pregnancy as research group, 50 normal pregnancy patients as control group. Then we detected the results of transvaginal ultrasound examination and serum 13-HCG ,progesterone levels for all patients, and analyzed the diagnostic accordance rate of three methods for detection at the same time. Results The β-HCG and progesterone values of research group were significantly lower than the control group（all P〈 0.05）, and the β-HCG after 48 h of control group rose significantly higher than that of the research group, reaching 1.96 times;according to the results of vaginal ultrasound examination,the endometrial thickness and accessory bag piece size of research group significantly larger than the control group （all P〈0. 05） ,while the research group＇s pelvic cavity accumulates fluid content was slightly higher than the control group,but there was no significant difference （P〉0.05）. The diagnostic accordance rate of transvaginal ultrasonography ＋ Serum β-HCG q-progesterone were both significantly higher than that of single serum β-HCG, proges- terone and endometrial thickness in two groups （P〈0. 05）. Conclusion The application of combining vaginal ultrasound, serum β-HCG and progesterone, which can effectively improve the diagnostic rate of early tubal pregnancy, should be promoted and popularized in clinic.