腹腔镜下阴道延长及卵巢移位在年轻宫颈癌患者中的应用效果分析

Effect analysis of laparoscopic vaginal extension and the ovarian shift in young patients with cervical cancer

目的:观察腹腔镜下阴道延长及卵巢移位在年轻宫颈癌患者中的应用效果。方法:将118例宫颈癌患者随机分为对照组与观察组,对照组行开腹全子宫切除+卵巢移位+阴道延长术,观察组行腹腔镜全子宫切除+卵巢移位+阴道延长术。对比两组患者手术情况、阴道长度、卵巢激素水平、性生活改善情况。结果:观察组术中出血量显著少于对照组(P<0.05),两组手术时间、切除淋巴结数量及治疗前后阴道长度差异无统计学意义(P>0.05)。两组治疗后6个月黄体生成素(luteinizing hormone,LH)、雌二醇(estradiol,E_2)、卵泡刺激素(follicle-stimulating hormone,FSH)均在正常范围内,差异均无统计学意义(P>0.05)。观察组性生活满意比例高于对照组,差异有统计学意义(P<0.05)。结论:年轻宫颈癌患者行腹腔镜阴道延长及卵巢移位术可有效保留卵巢及阴道功能,提高患者术后性生活质量,促进卵巢激素水平恢复,值得临床推广应用。

Objective ： To observe the effect of laparoscopic vaginal extension and the ovarian shift in young patients with cervical cancer. Methods ： One hundred and eighteen patients with cervical cancer were randomly divided into control group and observation group, control group underwent the open hysterectomy ＋ ovary shift ＋ vaginal extension, observation group underwent laparoscopic total hysterectomy ＋ ovary shift ＋ vaginal extension. The surgical conditions, vaginal length, ovarian hormone levels, improvement of sexual life of two groups were compared. Results：The intraoperative blood loss of observation group was significantly less than that of the control group, the operative time, harvested lymph node and vaginal length before and after the treatment in the two groups were not statistically significantly different （ P 〉 0.05 ）. The luteinizing hormone （ LH ）, estradiol （ E2 ）, follicle-stimulating hormone （FSH） of two groups in 6 months after treatment were within the normal range, there were no statistically significant differences （ P 〉 0.05 ）. The sex life satisfaction rate of observation group was higher than that of the control group, the difference was statistically significant （ P 〈 0.05 ）. Conclusions：Laparoscopic vaginal extension and ovarian transposition for young patients with cervical cancer can effectively keep the ovary and vaginal functions, improve the postoperative quality of sexual life, promote recovery of ovarian hormone levels, this procedure is worthy of clinical popularization and application.